1989
Technetium-99m hexakis 2-methoxyisobutyl isonitrile: human biodistribution, dosimetry, safety, and preliminary comparison to thallium-201 for myocardial perfusion imaging.
Wackers F, Berman D, Maddahi J, Watson D, Beller G, Strauss H, Boucher C, Picard M, Holman B, Fridrich R. Technetium-99m hexakis 2-methoxyisobutyl isonitrile: human biodistribution, dosimetry, safety, and preliminary comparison to thallium-201 for myocardial perfusion imaging. Journal Of Nuclear Medicine 1989, 30: 301-11. PMID: 2525610.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseArtery diseaseMulticenter phase II clinical trialSignificant coronary artery diseasePhase II clinical trialMulticenter phase IStress imagesMyocardial perfusion imagingNew myocardial imaging agentHuman biodistributionClinical efficacyClinical trialsMyocardial analysisStress imagingMyocardial imaging agentMyocardial uptakeMyocardial segmentsNormal volunteersThallium-201Myocardial imagingPerfusion imagingPatientsPhase IExact concordanceMyocardial images
1983
Gold-195m for serial first pass radionuclide angiocardiography during upright exercise in patients with coronary artery disease
Wackers F, Stein R, Pytlik L, Plankey M, Lange R, Hoffer P, Sands M, Zaret B, Berger H. Gold-195m for serial first pass radionuclide angiocardiography during upright exercise in patients with coronary artery disease. Journal Of The American College Of Cardiology 1983, 2: 497-505. PMID: 6875113, DOI: 10.1016/s0735-1097(83)80277-0.Peer-Reviewed Original ResearchConceptsVentricular ejection fractionLeft ventricular ejection fractionCoronary artery diseaseLeft ventricular functionFirst-pass radionuclide angiocardiographyEjection fractionArtery diseaseVentricular functionRadionuclide angiocardiographyVentricular ejection fraction responseThallium-201 myocardial imagingThallium-201 stress scintigraphyLeft ventricular reserveEjection fraction responseSame exercise testThallium-201 myocardial imagesMulticrystal gamma cameraFirst-pass studiesSerial exerciseVentricular reserveGamma cameraLow radiation dosePeak exerciseUpright exerciseStress scintigraphy
1982
Gold-195m, a new generator-produced short-lived radionuclide for sequential assessment of ventricular performance by first pass radionuclide angiocardiography
Wackers F, Giles R, Hoffer P, Lange R, Berger H, Zaret B, Pytlik L, Plankey M. Gold-195m, a new generator-produced short-lived radionuclide for sequential assessment of ventricular performance by first pass radionuclide angiocardiography. The American Journal Of Cardiology 1982, 50: 89-94. PMID: 7046410, DOI: 10.1016/0002-9149(82)90013-3.Peer-Reviewed Original Research