1995
Myocardial perfusion imaging with 99mTc tetrofosmin. Comparison to 201Tl imaging and coronary angiography in a phase III multicenter trial. Tetrofosmin International Trial Study Group.
Zaret B, Rigo P, Wackers F, Hendel R, Braat S, Iskandrian A, Sridhara B, Jain D, Itti R, Serafini A, Goris M, Lahiri A. Myocardial perfusion imaging with 99mTc tetrofosmin. Comparison to 201Tl imaging and coronary angiography in a phase III multicenter trial. Tetrofosmin International Trial Study Group. Circulation 1995, 91: 313-9. PMID: 7805233, DOI: 10.1161/01.cir.91.2.313.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseArtery diseaseTetrofosmin imagingCoronary angiographyMyocardial perfusionTetrofosmin imagesHealthy subjectsPhase III multicenter trialConventional myocardial perfusionLower likelihoodCentral core laboratoryMyocardial perfusion abnormalitiesNew 99mTcPeak heart rateNegative predictive accuracyMyocardial perfusion imagingNew myocardial imaging agentPlanar 201TlMulticenter trialNormalcy rateCoronary angiogramDouble productPerfusion abnormalitiesMyocardial imaging agentRadiotracer injection
1993
Biokinetics of technetium-99m-tetrofosmin: myocardial perfusion imaging agent: implications for a one-day imaging protocol.
Jain D, Wackers FJ, Mattera J, McMahon M, Sinusas AJ, Zaret BL. Biokinetics of technetium-99m-tetrofosmin: myocardial perfusion imaging agent: implications for a one-day imaging protocol. Journal Of Nuclear Medicine 1993, 34: 1254-9. PMID: 8326381.Peer-Reviewed Original ResearchConceptsOrgan ratiosGastrointestinal tractRest imagesImaging protocolSymptom-limited treadmill exerciseDecay-corrected countsLeft anterior oblique viewStress imagesAnterior oblique viewPortion of liverOptimal imaging protocolMyocardial perfusion imaging agentPeak exerciseTreadmill exerciseClinical trialsTechnetium-99mRadiotracer injectionMyocardial perfusionTetrofosmin imagesGallbladderPhase IEntire heartLiverTractOblique view