1986
Effects of Cyclosporine and Cortisone on the Pathogenesis of Primary Infection with Cytomegalovirus in the Guinea Pig
MacGregor M, Lucia H, Vine W, FitzGerald P, Bia F. Effects of Cyclosporine and Cortisone on the Pathogenesis of Primary Infection with Cytomegalovirus in the Guinea Pig. The Journal Of Infectious Diseases 1986, 153: 503-510. PMID: 3005426, DOI: 10.1093/infdis/153.3.503.Peer-Reviewed Original ResearchConceptsPrimary infectionGuinea pigsTissue culture infectious dosesEffect of cyclosporineGuinea pig modelRate of isolationGuinea pig cytomegalovirusOral CsAImmunosuppressive agentsInflammatory responseInfectious dosesViral inclusionsPig modelDay 14Day 0CortisoneCytomegalovirusMinimal inflammatory responseCsALymphopeniaPathogenesisInfectionUntreated controlsAnimalsTissue
1984
Vaccination Against Transplacental Cytomegalovirus Transmission: Vaccine Reactivation and Efficacy in Guinea Pigs
Bia F, Miller S, Lucia H, Griffith B, Tarsio M, Hsiung G. Vaccination Against Transplacental Cytomegalovirus Transmission: Vaccine Reactivation and Efficacy in Guinea Pigs. The Journal Of Infectious Diseases 1984, 149: 355-362. PMID: 6325549, DOI: 10.1093/infdis/149.3.355.Peer-Reviewed Original ResearchConceptsCMV infectionSubsequent pregnancyThroat swabsCMV transmissionGuinea pigsNonpregnant control animalsCongenital CMV infectionTissue culture infective dosesHartley strain guinea pigsGuinea pig modelCMV vaccineCytomegalovirus transmissionCytomegalovirus infectionFetal infectionPregnant controlsAcute viremiaGeneralized infectionCytomegalovirus vaccineControl animalsInfective dosesPregnancyPregnant animalsVaccineInfectionSwabs
1982
Neutrophil response and function during acute cytomegalovirus infection in guinea pigs
Yourtee E, Bia F, Griffith B, Root R. Neutrophil response and function during acute cytomegalovirus infection in guinea pigs. Infection And Immunity 1982, 36: 11-16. PMID: 6281184, PMCID: PMC351177, DOI: 10.1128/iai.36.1.11-16.1982.Peer-Reviewed Original ResearchConceptsAcute cytomegalovirus infectionTissue culture infective dosesCytomegalovirus infectionPolymorphonuclear leukocytesGuinea pig cytomegalovirusPeritoneal polymorphonuclear leukocytesGuinea pigsInfected animalsInflammatory stimuliUninfected controlsInfective dosesHartley strain guinea pigsType of infectionPhorbol myristate acetateAcute infectionGranulocyte numbersNeutrophil responseCasein injectionNeutrophil activatorInflammatory sitesBacterial stimuliControl animalsBone marrowDecreased mobilizationBacterial killing
1981
Cytomegalovirus-induced mononucleosis in guinea pigs
Griffith B, Lucia H, Bia F, Hsiung G. Cytomegalovirus-induced mononucleosis in guinea pigs. Infection And Immunity 1981, 32: 857-863. PMID: 6265366, PMCID: PMC351522, DOI: 10.1128/iai.32.2.857-863.1981.Peer-Reviewed Original ResearchConceptsGuinea pigsAcute infectionLymphoid tissueBone marrowB-lymphocyte-enriched populationsTransient hematological changesB-cell areasCMV mononucleosisAtypical lymphocytesCMV infectionCytomegalovirus infectionLymph nodesBlood countMononuclear cellsChronic infectionSpleen sizeHematological changesSplenic macrophagesVirus persistenceVirus inoculationInfectionBlood parametersVirus distributionMononucleosisSpleen