1987
Thymic hypoplasia, splenomegaly and immune depression in guinea pigs with neonatal cytomegalovirus infection
Zheng Z, Lavallee J, Bia F, Griffith B. Thymic hypoplasia, splenomegaly and immune depression in guinea pigs with neonatal cytomegalovirus infection. Developmental & Comparative Immunology 1987, 11: 407-418. PMID: 3040485, DOI: 10.1016/0145-305x(87)90084-x.Peer-Reviewed Original ResearchConceptsGuinea pigsCMV infectionCytomegalovirus infectionThymic hypoplasiaProliferative responseImmune proliferative responsesNeonatal cytomegalovirus infectionAcute CMV infectionT lymphocyte populationsNeonatal guinea pigsT cell mitogensConcanavalin AB cell mitogensImmunodepressive effectImmune depressionLymphocyte populationsSpleen cellsInfectious virusGrowth retardationDissimilar alterationsHigh titersSpleenInfectionThymusSplenomegaly
1981
Cytomegalovirus-induced mononucleosis in guinea pigs
Griffith B, Lucia H, Bia F, Hsiung G. Cytomegalovirus-induced mononucleosis in guinea pigs. Infection And Immunity 1981, 32: 857-863. PMID: 6265366, PMCID: PMC351522, DOI: 10.1128/iai.32.2.857-863.1981.Peer-Reviewed Original ResearchConceptsGuinea pigsAcute infectionLymphoid tissueBone marrowB-lymphocyte-enriched populationsTransient hematological changesB-cell areasCMV mononucleosisAtypical lymphocytesCMV infectionCytomegalovirus infectionLymph nodesBlood countMononuclear cellsChronic infectionSpleen sizeHematological changesSplenic macrophagesVirus persistenceVirus inoculationInfectionBlood parametersVirus distributionMononucleosisSpleen