2023
Transcriptomic identification of genes expressed in invasive S. aureus diabetic foot ulcer infection
Agidigbi T, Kwon H, Knight J, Zhao D, Lee F, Oh I. Transcriptomic identification of genes expressed in invasive S. aureus diabetic foot ulcer infection. Frontiers In Cellular And Infection Microbiology 2023, 13: 1198115. PMID: 37434783, PMCID: PMC10332306, DOI: 10.3389/fcimb.2023.1198115.Peer-Reviewed Original ResearchConceptsDiabetic foot ulcersPeripheral blood mononuclear cellsHost immune responseActive infectionImmune responseDiabetic foot ulcer infectionsInfected diabetic foot ulcersFoot ulcer infectionsPatients 8 weeksIntravenous antibiotic therapyBlood mononuclear cellsWound healing statusDFU infectionsPBMC expressionSalvage therapyUlcer infectionDifferent time pointsAntibiotic therapyMajor complicationsSurgical treatmentFoot ulcersMononuclear cellsPotential intervention optionsSpecies-specific infectionTreatment response
2005
Zoledronate induces apoptosis in cells from fibro‐cellular membrane of unicameral bone cyst (UBC)
Yu J, Chang S, Suratwala S, Chung W, Abdelmessieh P, Lee H, Yang J, Lee F. Zoledronate induces apoptosis in cells from fibro‐cellular membrane of unicameral bone cyst (UBC). Journal Of Orthopaedic Research® 2005, 23: 1004-1012. PMID: 15921873, DOI: 10.1016/j.orthres.2005.02.012.Peer-Reviewed Original ResearchConceptsUnicameral bone cystsPeripheral blood mononuclear cellsBlood mononuclear cellsTrabecular bone cellsBone cystUBC cellsMononuclear cellsBone cellsZoledronate concentrationsIsolated peripheral blood mononuclear cellsImmunohisto/cytochemistryPercutaneous injection therapyAnti-resorptive agentsAnti-osteoclastogenic effectApoptotic fractionSTRO-1Potential therapeutic effectsPotential therapeutic roleEffect of zoledronateBenign cystic lesionsNitrogen-containing bisphosphonatesDose-dependent mannerOsteoclast-like cellsInjection therapyPathologic fracture