2020
Early Increased Urinary IL-2 and IL-10 Levels Were Associated With Development of Chronic UTI in a Murine Model
Zhu K, Hill WG, Li F, Shi B, Chai TC. Early Increased Urinary IL-2 and IL-10 Levels Were Associated With Development of Chronic UTI in a Murine Model. Urology 2020, 141: 188.e1-188.e6. PMID: 32201154, DOI: 10.1016/j.urology.2020.03.015.Peer-Reviewed Original ResearchConceptsChronic urinary tract infectionUrinary tract infectionCytokines/chemokinesIL-2IL-10Enzyme-linked immunosorbent assayBacterial loadInflammatory cytokines/chemokinesTissue bacterial loadUrinary IL-2IL-10 levelsDays post infectionUTI susceptibilityTract infectionsMurine modelUTI infectionsPost infectionVoiding behaviorChemokinesMiceImmunosorbent assayResistant groupInfectionSignificant differencesDpi
2007
A Novel Pathway That Regulates Inflammatory Disease in the Respiratory Tract
Niu N, Le Goff MK, Li F, Rahman M, Homer RJ, Cohn L. A Novel Pathway That Regulates Inflammatory Disease in the Respiratory Tract. The Journal Of Immunology 2007, 178: 3846-3855. PMID: 17339484, DOI: 10.4049/jimmunol.178.6.3846.Peer-Reviewed Original ResearchConceptsAirway inflammationInflammatory diseasesRespiratory tractTh2-induced airway inflammationChronic airway inflammatory diseaseLymphocyte-deficient miceState of immunosuppressionAcute airway inflammationAirway inflammatory diseasesEffector Th cellsTh2 cells resultsAirway hyperresponsivenessInflammation wanesTh2 modelEffector Th1Respiratory illnessTh cellsInhalational exposureInflammationInhibitory effectSuch diseasesDiseaseStriking inhibitionTh1Localized treatment