Leptin Signaling and Hyperparathyroidism: Clinical and Genetic Associations
Hoang D, Broer N, Roman SA, Yao X, Abitbol N, Li F, Sosa JA, Sue GR, DeWan AT, Wong ML, Licinio J, Simpson C, Li AY, Pizzoferrato N, Narayan D. Leptin Signaling and Hyperparathyroidism: Clinical and Genetic Associations. Journal Of The American College Of Surgeons 2013, 218: 1239-1250.e4. PMID: 24468228, DOI: 10.1016/j.jamcollsurg.2013.11.013.Peer-Reviewed Original ResearchConceptsParathyroid hormone levelsLeptin levelsParathyroid glandsHormone levelsBaseline leptin levelsLarge parathyroid glandsBody mass indexRole of leptinWilcoxon signed-rank testHyperplasia subgroupsParathyroid sizeObese patientsPostoperative changesMass indexParathyroid adenomaProspective studyParathyroid tissueBland-Altman methodLeptin productionSigned-rank testSurgical conditionsClinical studiesLeptin signalingLEPR polymorphismsLeptin