2024
Macro- and microvascular contributions to cerebral structural alterations in patients with asymptomatic carotid artery stenosis
Schmitzer L, Kaczmarz S, Göttler J, Hoffmann G, Kallmayer M, Eckstein H, Hedderich D, Kufer J, Zimmer C, Preibisch C, Hyder F, Sollmann N. Macro- and microvascular contributions to cerebral structural alterations in patients with asymptomatic carotid artery stenosis. Cerebrovascular And Brain Metabolism Reviews 2024, 44: 1629-1642. PMID: 38506325, PMCID: PMC11418673, DOI: 10.1177/0271678x241238935.Peer-Reviewed Original ResearchInternal carotid artery stenosisInternal carotid artery stenosis patientsCerebral blood flowCarotid artery stenosisPeak width of skeletonized mean diffusivitySmall vessel diseaseContralateral alterationsArtery stenosisAsymptomatic internal carotid artery stenosisWhite matterAsymptomatic carotid artery stenosisCapillary transit time heterogeneityCerebral structural alterationsCortical thicknessMagnetic resonance imagingHemodynamic alterationsRisk factorsPatientsDTI metricsResonance imagingDorsal cingulate cortexBlood flowIschemic strokeMean diffusivityStenosis
2011
Neuroanatomical changes in a mouse model of early life neglect
Duque A, Coman D, Carlyle BC, Bordner KA, George ED, Papademetris X, Hyder F, Simen AA. Neuroanatomical changes in a mouse model of early life neglect. Brain Structure And Function 2011, 217: 459-472. PMID: 21984312, PMCID: PMC3664301, DOI: 10.1007/s00429-011-0350-9.Peer-Reviewed Original ResearchConceptsMouse modelNeuroanatomical changesEarly life neglectNovel mouse modelNovel animal modelWhite matter disorganizationMaternal separationCortical thicknessAdult miceAnimal modelsBehavioral abnormalitiesInter-hemispheric asymmetrySmall brain sizeSubcortical structuresPharmacological experimentationProtein expressionLeft hemisphereEarly weaningHuman survivorsAbnormalitiesCurrent knowledgeBrain sizeConcomitant changesAtrophy