2023
Autism spectrum disorder-specific changes in white matter connectome edge density based on functionally defined nodes
Weber C, Lake E, Haider S, Mozayan A, Bobba P, Mukherjee P, Scheinost D, Constable R, Ment L, Payabvash S. Autism spectrum disorder-specific changes in white matter connectome edge density based on functionally defined nodes. Frontiers In Neuroscience 2023, 17: 1285396. PMID: 38075286, PMCID: PMC10702224, DOI: 10.3389/fnins.2023.1285396.Peer-Reviewed Original ResearchWhite matterPositive symptom correlationAutism spectrum disorderSymptom severity scoresBetween-group differencesAbnormal connectivity patternsCortical nodesVoxel-wise analysisDiffusion tensor imagingSeverity scoreWM fiber tractsSymptom correlationClinical dataConnectome disruptionConnectome changesEarly changesCortical regionsInfantsED reductionWM disruptionDisorder-specific changesTensor imagingFunctional imagingFiber tractsProbabilistic tractography
2016
Altered intracortical myelin staining in the dorsolateral prefrontal cortex in severe mental illness
Lake EMR, Steffler EA, Rowley CD, Sehmbi M, Minuzzi L, Frey BN, Bock NA. Altered intracortical myelin staining in the dorsolateral prefrontal cortex in severe mental illness. European Archives Of Psychiatry And Clinical Neuroscience 2016, 267: 369-376. PMID: 27629158, DOI: 10.1007/s00406-016-0730-5.Peer-Reviewed Original ResearchConceptsMajor depressive disorderSevere mental illnessMiddle frontal gyrusBipolar disorderDorsolateral prefrontal cortexMental illnessWhite matterIntracortical myelinDiagnosis of MDDPrefrontal cortexDeep white matter tractsDeep white matterTissue attenuationSuperficial white matterAmount of myelinWhite matter tractsCerebral cortexDepressive disorderFast BlueMyelinated fibersPsychiatric illnessMyelin stainingIllnessCortexCortical depth