Prospective plasma efavirenz concentration assessment in Chinese HIV‐infected adults enrolled in a large multicentre study
Guo F, Cheng X, Hsieh E, Du X, Fu Q, Peng W, Li Y, Song X, Routy J, Li T. Prospective plasma efavirenz concentration assessment in Chinese HIV‐infected adults enrolled in a large multicentre study. HIV Medicine 2018, 19: 440-451. PMID: 29761920, PMCID: PMC6538474, DOI: 10.1111/hiv.12607.Peer-Reviewed Original ResearchLower body weightEfavirenz concentrationsBody weightWeek 4Chinese HIVMedian efavirenz concentrationPlasma efavirenz concentrationsAntiretroviral therapy initiationProspective multicentre trialProportion of patientsLarge multicentre studyPlasma samplesMultivariable regression analysisHigh efavirenz concentrationsNon-Han ethnicityEfavirenz 600Therapy initiationMulticentre trialMulticentre studyDosage reductionOptimal dosingTherapeutic windowPatientsSubstantial proportionHIV