2018
Associations between children’s family environment, spontaneous brain oscillations, and emotional and behavioral problems
Sato J, Biazoli C, Salum G, Gadelha A, Crossley N, Vieira G, Zugman A, Picon F, Pan P, Hoexter M, Amaro E, Anés M, Moura L, Del’Aquilla M, Mcguire P, Rohde L, Miguel E, Bressan R, Jackowski A. Associations between children’s family environment, spontaneous brain oscillations, and emotional and behavioral problems. European Child & Adolescent Psychiatry 2018, 28: 835-845. PMID: 30392120, DOI: 10.1007/s00787-018-1240-y.Peer-Reviewed Original ResearchConceptsFamily environmentMental health outcomesFamily coherenceEmotional problemsOrbitofrontal cortexTemporal poleResting-state fMRI dataLeft temporal poleSpontaneous brain oscillationsChild's family environmentRight orbitofrontal cortexOscillatory neural activityHealth outcomesBrain oscillationsBehavioral problemsNeural activityFMRI dataFMRI metricsBrain areasLow-frequency fluctuationsFractional amplitudeLower incidenceSpontaneous activityHigh incidenceExploratory study
2007
Resistência e refratariedade no transtorno obsessivo-compulsivo
Ferrão Y, Diniz J, Lopes A, Shavitt R, Greenberg B, Miguel E. Resistência e refratariedade no transtorno obsessivo-compulsivo. Brazilian Journal Of Psychiatry 2007, 29: s66-s76. PMID: 18172943, DOI: 10.1590/s1516-44462006005000059.Peer-Reviewed Original ResearchMeSH KeywordsAntidepressive AgentsAntipsychotic AgentsBehavior TherapyClinical Trials as TopicCombined Modality TherapyDrug ResistanceDrug ToleranceFamily RelationsHumansMeta-Analysis as TopicObsessive-Compulsive DisorderPsychiatric Status Rating ScalesPsychotherapySelective Serotonin Reuptake InhibitorsConceptsObsessive-compulsive disorder patientsObsessive-compulsive disorderTherapeutic alternativeDisorder patientsConventional treatmentEffective therapeutic alternativeCompulsive disorder patientsAvailable treatmentsTreatment responseClinical challengeTreatment resistanceSymptom remissionAdequate treatmentPatient sufferingPatientsCurrent conceptsRemissionMore studiesTreatmentDisordersSignificant numberLiterature reviewUnanswered questionsExtrinsic factors