1998
Lyme Arthritis in Children: Clinical Epidemiology and Long-term Outcomes
Gerber M, Zemel L, Shapiro E. Lyme Arthritis in Children: Clinical Epidemiology and Long-term Outcomes. Pediatrics 1998, 102: 905-908. PMID: 9755263, DOI: 10.1542/peds.102.4.905.Peer-Reviewed Original ResearchConceptsLong-term outcomesLyme arthritisAppropriate antimicrobial therapyAntimicrobial therapyClinical epidemiologyLyme diseaseMean white blood cell countWhite blood cell countNewington Children's HospitalCells/mm3Pediatric rheumatology clinicTime of diagnosisEarly Lyme diseaseErythrocyte sedimentation rateLong-term followOnset of symptomsBlood cell countStructured telephone interviewActive arthritisChronic arthritisRheumatology clinicArthroscopic synovectomyInitial diagnosisChildren's HospitalTelephone follow
1992
A Controlled Trial of Antimicrobial Prophylaxis for Lyme Disease after Deer-Tick Bites
Shapiro E, Gerber M, Holabird N, Berg A, Feder H, Bell G, Rys P, Persing D. A Controlled Trial of Antimicrobial Prophylaxis for Lyme Disease after Deer-Tick Bites. New England Journal Of Medicine 1992, 327: 1769-1773. PMID: 1435930, DOI: 10.1056/nejm199212173272501.Peer-Reviewed Original ResearchConceptsDeer tick biteRisk of infectionProphylactic antimicrobial treatmentLyme diseaseB. burgdorferiAntimicrobial treatmentDeer ticksPlacebo-controlled trialPlacebo-treated subjectsCare of personsAsymptomatic seroconversionAntimicrobial prophylaxisErythema migransClinical manifestationsPolymerase chain reactionLate manifestationPlaceboDiseaseSerum samplesInfectionBorrelia burgdorferiBiteChain reactionAmoxicillinBurgdorferiA Prospective Study of Recurrent Febrile Seizures
Berg A, Shinnar S, Hauser W, Alemany M, Shapiro E, Salomon M, Crain E. A Prospective Study of Recurrent Febrile Seizures. New England Journal Of Medicine 1992, 327: 1122-1127. PMID: 1528207, DOI: 10.1056/nejm199210153271603.Peer-Reviewed Original ResearchConceptsRisk of recurrenceRecurrent febrile seizuresFebrile seizuresProspective studyFamily historyFirst febrile seizureDuration of feverPredictors of recurrenceComplex febrile seizuresInitial febrile seizurePediatric emergency departmentInitial seizureEmergency departmentMedical recordsNeurodevelopmental abnormalitiesCumulative riskRecurrenceFeverSeizuresDegree of increaseDegrees FChildrenRiskShort durationMonths
1986
Clinical features as predictors of functional status in children with cystic fibrosis
Katz J, Horwitz R, Dolan T, Shapiro E. Clinical features as predictors of functional status in children with cystic fibrosis. The Journal Of Pediatrics 1986, 108: 352-358. PMID: 3950815, DOI: 10.1016/s0022-3476(86)80872-1.Peer-Reviewed Original ResearchConceptsCystic fibrosisClinical courseClinical featuresGood clinical courseValuable prognostic indicatorPrevious clinical studiesClinical deteriorationGastrointestinal symptomsPrognostic indicatorFunctional statusClinical studiesRespiratory diseaseSurvival rateFibrosisPatientsDiagnosisSubsequent outcomesSubsequent survival ratesChildrenSymptomsOutcomesSubstantial variabilityInitial levelMorbidityYears