Molecular characterization of the humoral response to the 41-kilodalton flagellar antigen of Borrelia burgdorferi, the Lyme disease agent
Berland R, Fikrig E, Rahn D, Hardin J, Flavell RA. Molecular characterization of the humoral response to the 41-kilodalton flagellar antigen of Borrelia burgdorferi, the Lyme disease agent. Infection And Immunity 1991, 59: 3531-3535. PMID: 1894359, PMCID: PMC258917, DOI: 10.1128/iai.59.10.3531-3535.1991.Peer-Reviewed Original ResearchConceptsLyme diseaseHumoral responseLate-stage Lyme diseaseEarly humoral responseBorrelia burgdorferiFlagellar antigensPolymerase chain reactionSerological testingImmunodominant domainWestern blotPatientsLyme disease agentAntigenDiseaseChain reactionGlutathione S-transferaseFusion proteinAffinity-purified fusion proteinFlagellin fragmentBacterial flagellinSerumBurgdorferiS-transferaseDisease agentsMolecular characterization