Elimination of Borrelia burgdorferi from vector ticks feeding on OspA-immunized mice.
Fikrig E, Telford SR, Barthold SW, Kantor FS, Spielman A, Flavell RA. Elimination of Borrelia burgdorferi from vector ticks feeding on OspA-immunized mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 1992, 89: 5418-5421. PMID: 1608951, PMCID: PMC49303, DOI: 10.1073/pnas.89.12.5418.Peer-Reviewed Original ResearchConceptsRecombinant outer surface protein AVaccine-induced immunityIxodes dammini ticksSurface protein AOuter surface protein ANonimmunized miceImmunized miceSpirochetal infectionTick biteCharacteristic histopathologyImmunized animalsLyme diseaseMiceBorrelia burgdorferiSpirochetesMode of protectionVector ticksOspATicksProtein AHistopathologyInfectionDiseaseImmunity