2008
A Differential Role for BB0365 in the Persistence of Borrelia burgdorferi in Mice and Ticks
Pal U, Dai J, Li X, Neelakanta G, Luo P, Kumar M, Wang P, Yang X, Anderson JF, Fikrig E. A Differential Role for BB0365 in the Persistence of Borrelia burgdorferi in Mice and Ticks. The Journal Of Infectious Diseases 2008, 197: 148-155. PMID: 18171298, DOI: 10.1086/523764.Peer-Reviewed Original ResearchConceptsVertebrate hostsWild-type B. burgdorferiArthropod vectorsB. burgdorferi persistenceB. burgdorferi transcriptomeDiverse murine tissuesSpirochete life cycleLife cycleB. burgdorferi B31Lyme disease agentGene productsMurine tissuesGenesWild rodentsDisease agentsDifferential rolesFeeding ticksB. burgdorferiInfectious isolatesHostBorrelia burgdorferiTicksTranscriptomePersistence of BorreliaMutants
2007
Tick–host–pathogen interactions in Lyme borreliosis
Hovius JW, van Dam AP, Fikrig E. Tick–host–pathogen interactions in Lyme borreliosis. Trends In Parasitology 2007, 23: 434-438. PMID: 17656156, DOI: 10.1016/j.pt.2007.07.001.Peer-Reviewed Original ResearchConceptsVertebrate hostsB. burgdorferi survivalB. burgdorferi genesEnzootic life cycleSpirochete survivalGene productsB. burgdorferiArthropod vectorsGenesVector moleculesLife cycleDifferent environmentsHostBorrelia burgdorferiIxodes ticksTROSPATicksSpirochetal agentBurgdorferiLyme borreliosisMicrobesSalp15ExpressionSurvival
2003
Adaptation of Borrelia burgdorferi in the tick and the mammalian host
Anguita J, Hedrick MN, Fikrig E. Adaptation of Borrelia burgdorferi in the tick and the mammalian host. FEMS Microbiology Reviews 2003, 27: 493-504. PMID: 14550942, DOI: 10.1016/s0168-6445(03)00036-6.Peer-Reviewed Original ResearchConceptsMammalian hostsGene expressionRegulation of genesAdaptation of BorreliaGene productsDifferent environmentsArthropod vectorsEnzootic cycleCurrent knowledgeLife cycleHostExpressionCausative agentB. burgdorferiBorrelia burgdorferiGenesSpirochetesTicksBurgdorferiMicroorganismsGreater abilityRegulationLyme diseaseThorough understandingFunction