2017
Actin Filament Strain Promotes Severing and Cofilin Dissociation
Schramm AC, Hocky GM, Voth GA, Blanchoin L, Martiel JL, De La Cruz EM. Actin Filament Strain Promotes Severing and Cofilin Dissociation. Biophysical Journal 2017, 112: 2624-2633. PMID: 28636918, PMCID: PMC5479148, DOI: 10.1016/j.bpj.2017.05.016.Peer-Reviewed Original ResearchConceptsContinuum mechanics modelStrain energy distributionMechanical propertiesMechanics modelFilament twistingEnhanced spatial resolutionFilament mechanical propertiesElastic energyTorsional rigidityShape deformationSpatial resolutionContinuum modelTorsional flexibilityFilament bendingCofilactin filamentsDynamics simulationsMolecular dynamics simulationsBucklingCofilin-decorated segmentsDeformationBendingBoundariesEnergy distributionLoadFilament model
2010
Origin of Twist-Bend Coupling in Actin Filaments
De La Cruz EM, Roland J, McCullough BR, Blanchoin L, Martiel JL. Origin of Twist-Bend Coupling in Actin Filaments. Biophysical Journal 2010, 99: 1852-1860. PMID: 20858430, PMCID: PMC2941021, DOI: 10.1016/j.bpj.2010.07.009.Peer-Reviewed Original Research