BIN1 localization is distinct from Tau tangles in Alzheimer's disease.
De Rossi P, Buggia-Prevot V, Andrew RJ, Krause SV, Woo E, Nelson PT, Pytel P, Thinakaran G. BIN1 localization is distinct from Tau tangles in Alzheimer's disease. Matters 2017, 2017 PMID: 29479533, PMCID: PMC5823513, DOI: 10.19185/matters.201611000018.Peer-Reviewed Original ResearchTangle pathologyHuman ADBIN1 expressionNeurofibrillary tangle pathologyBrains of patientsSubset of neuronsRisk factor genesAD brainNeurofibrillary tanglesTau tanglesPeripheral tissuesSenile plaquesTau propagationPathological lesionsWhite matterAlzheimer's diseaseMature oligodendrocytesGray matterCellular markersBrainCellular expressionComplex cellular mechanismsInverse correlationCellular mechanismsDisease