2013
Clonal Astrocytic Response to Cortical Injury
Martín-López E, García-Marques J, Núñez-Llaves R, López-Mascaraque L. Clonal Astrocytic Response to Cortical Injury. PLOS ONE 2013, 8: e74039. PMID: 24040158, PMCID: PMC3769363, DOI: 10.1371/journal.pone.0074039.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAstrocytesBiomarkersBrain InjuriesCell ProliferationCerebral CortexClone CellsDisease Models, AnimalElectroporationHypertrophyMiceConceptsDays post injuryHigher proliferative responsesCentral nervous systemCortical injuryStrong morphological alterationsAstrocytic responsePost injuryBrain injuryGlial functionGlial cellsProliferative responseImmunohistochemical analysisNervous systemAstrocyte heterogeneitySame cloneInjuryMechanical injuryAstrocytesMorphological alterationsClonal responseHeterogeneous populationDistinct clonesCell lineagesMorphological changesMultifaceted roleInfluence of Chitosan Concentration on Cell Viability and Proliferation in Vitro by Changing Film Topography
Martín-López E, Nieto-Díaz M, Nieto-Sampedro M. Influence of Chitosan Concentration on Cell Viability and Proliferation in Vitro by Changing Film Topography. Journal Of Applied Biomaterials & Functional Materials 2013, 11: 151-158. PMID: 23413128, DOI: 10.5301/jabfm.2012.10449.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell LineCell ProliferationCell SurvivalChitosanMicroscopy, Atomic ForcePC12 CellsRatsSurface PropertiesTissue EngineeringConceptsChitosan filmsAtomic force microscopyFilm topographyTissue engineering applicationsChitosan concentrationPolymer surface topographyNeural tissue engineeringEnvironmental scanning electron microscopyScanning electron microscopyEngineering applicationsSurface topographyTissue engineeringAFM profilesFilmsForce microscopyTopography changesVitro biological propertiesChitosan solutionElectron microscopyChitosan polymerAlkaline precipitationNatural polysaccharidesTopographyPropertiesBridge
2012
Chitosan, Gelatin and Poly(L-Lysine) Polyelectrolyte-Based Scaffolds and Films for Neural Tissue Engineering
Martín-López E, Alonso FR, Nieto-Díaz M, Nieto-Sampedro M. Chitosan, Gelatin and Poly(L-Lysine) Polyelectrolyte-Based Scaffolds and Films for Neural Tissue Engineering. Journal Of Biomaterials Science Polymer Edition 2012, 23: 207-232. PMID: 21192838, DOI: 10.1163/092050610x546426.Peer-Reviewed Original ResearchConceptsNeural tissue engineeringTissue engineeringG filmsSmall pore sizeThermal resistancePore sizeSuitable materialBiomaterial implantsFilmsBest mixturePromising candidateEngineeringDorsal root gangliaDifferent physicochemical approachesDistinct electrostatic interactionsTraumatic nerve damageSpindle cell morphologyGel morphologyGlial cell growthNerve damage
2010
Peripheral contributions to olfactory bulb cell populations (migrations towards the olfactory bulb)
Blanchart A, Martín‐López E, De Carlos JA, López‐Mascaraque L. Peripheral contributions to olfactory bulb cell populations (migrations towards the olfactory bulb). Glia 2010, 59: 278-292. PMID: 21125652, DOI: 10.1002/glia.21100.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAnimalsAnimals, NewbornBromodeoxyuridineCell MovementCell ProliferationCells, CulturedEmbryo, MammalianFemaleGene Expression Regulation, DevelopmentalGene Transfer TechniquesGreen Fluorescent ProteinsMiceNerve Tissue ProteinsNeurogliaNeuronsOlfactory BulbOlfactory PathwaysPregnancyProsencephalonConceptsMigratory massCell populationsOlfactory axonsDifferent neural cell populationsOlfactory placodeOlfactory Ensheathing CellsCentral nervous systemLater postnatal stagesEmbryonic day 11Glial markersRetroviral injectionCNS neuronsNeural cell populationsGlomerular layerOlfactory nerveOlfactory bulbPeripheral contributionsNervous systemOlfactory epitheliumDifferent cell populationsDay 11Telencephalic vesiclePostnatal stagesInfected cellsOlfactory systemDifferential Adhesiveness and Neurite-promoting Activity for Neural Cells of Chitosan, Gelatin, and Poly-l-Lysine Films
Martín-López E, Nieto-Díaz M, Nieto-Sampedro M. Differential Adhesiveness and Neurite-promoting Activity for Neural Cells of Chitosan, Gelatin, and Poly-l-Lysine Films. Journal Of Biomaterials Applications 2010, 26: 791-809. PMID: 20876636, DOI: 10.1177/0885328210379928.Peer-Reviewed Original ResearchConceptsG filmsDorsal root gangliaTissue engineeringExcellent adhesive propertiesComposite filmsGood adhesionGood biomaterialFilmsPC12 cellsNGF-differentiated PC12 cellsC6 glioma cellsAdhesive propertiesRoot gangliaGlial cellsCerebral tissueHippocampal neuronsNerve repairMixture of CHGlioma cellsC6 lineTissue regenerationNeural cellsLysine filmsNeuronsEngineering