2023
How Bacterial Pathogens Coordinate Appetite with Virulence
Pokorzynski N, Groisman E. How Bacterial Pathogens Coordinate Appetite with Virulence. Microbiology And Molecular Biology Reviews 2023, 87: e00198-22. PMID: 37358444, PMCID: PMC10521370, DOI: 10.1128/mmbr.00198-22.Peer-Reviewed Original ResearchConceptsVirulence factorsTyphoid-like diseaseIntestinal inflammationFacultative intracellular pathogenImmunocompetent humansGut microbiotaPathogenic outcomesUtilization determinantsIntracellular pathogensSpecific nutrientsAntimicrobial agentsInfectionBacterial pathogensSerovar TyphimuriumBacterial virulencePathogensPathogenic traitsAnimal hostsPathwaySuch pathwaysCertain pathwaysMetabolic pathwaysVirulence programInflammationVirulence
2017
ATP-Dependent Persister Formation in Escherichia coli
Shan Y, Gandt A, Rowe S, Deisinger J, Conlon B, Lewis K, Zgurskaya H, Groisman E. ATP-Dependent Persister Formation in Escherichia coli. MBio 2017, 8: e02267-16. PMID: 28174313, PMCID: PMC5296605, DOI: 10.1128/mbio.02267-16.Peer-Reviewed Original ResearchConceptsChronic infectionFluorescence-activated cell sortingDrug toleranceATP levelsPersister formationDrug-tolerant persistersFluoroquinolone treatmentStress-induced activationSubpopulation of cellsLevels of ATPDormant variantsAntibiotic-tolerant cellsCellular ATP levelsBactericidal antibioticsDim cellsInfectionActivationPersister cellsAntibioticsCell sortingTreatmentSubpopulationsCellsActive toxinToxin activation
2000
Molecular mechanisms of Salmonella pathogenesis
Groisman EA, Mouslim C. Molecular mechanisms of Salmonella pathogenesis. Current Opinion In Infectious Diseases 2000, 13: 519-522. PMID: 11964823, DOI: 10.1097/00001432-200010000-00014.Peer-Reviewed Original Research
1998
At Least Four Percent of the Salmonella typhimurium Genome Is Required for Fatal Infection of Mice
Bowe F, Lipps C, Tsolis R, Groisman E, Heffron F, Kusters J. At Least Four Percent of the Salmonella typhimurium Genome Is Required for Fatal Infection of Mice. Infection And Immunity 1998, 66: 3372-3377. PMID: 9632607, PMCID: PMC108354, DOI: 10.1128/iai.66.7.3372-3377.1998.Peer-Reviewed Original Research
1987
Cloning of genes from members of the family Enterobacteriaceae with mini-Mu bacteriophage containing plasmid replicons
Groisman EA, Casadaban MJ. Cloning of genes from members of the family Enterobacteriaceae with mini-Mu bacteriophage containing plasmid replicons. Journal Of Bacteriology 1987, 169: 687-693. PMID: 3542967, PMCID: PMC211834, DOI: 10.1128/jb.169.2.687-693.1987.Peer-Reviewed Original ResearchConceptsSensitive recipient strainFamily EnterobacteriaceaeHigh phage titersC. freundiiProteus mirabilisPlasmid repliconsCitrobacter freundiiS. typhimuriumDrug-resistant transductantsSpecific mutationsMu derivativesE. coliSalmonella typhimuriumEnterobacteriaceaeFreundiiRecipient strainPhage titerTyphimuriumEscherichia coli bacteriophageInfectionTiters