1998
The ins and outs of virulence gene expression: Mg2+ as a regulatory signal
Groisman E. The ins and outs of virulence gene expression: Mg2+ as a regulatory signal. BioEssays 1998, 20: 96-101. PMID: 9504051, DOI: 10.1002/(sici)1521-1878(199801)20:1<96::aid-bies13>3.0.co;2-3.Peer-Reviewed Original ResearchConceptsSignal transduction systemTransduction systemCellular locationPhoP/PhoQ systemPathogen Salmonella enterica serovar TyphimuriumIntracellular pathogen Salmonella enterica serovar TyphimuriumTranscription of genesPhoP/PhoQVirulence gene expressionFacultative intracellular pathogen Salmonella enterica serovar TyphimuriumSalmonella enterica serovar TyphimuriumDifferent cell typesRegulatory hierarchyEnterica serovar TyphimuriumRegulatory signalsExtracellular environmentGene expressionHost cellsHost cuesCell typesMultiple environmentsSerovar TyphimuriumPrecise tissuePhoQTranscription
1995
Relationship between evolutionary rate and cellular location among the Inv/Spa invasion proteins of Salmonella enterica.
Li J, Ochman H, Groisman EA, Boyd EF, Solomon F, Nelson K, Selander RK. Relationship between evolutionary rate and cellular location among the Inv/Spa invasion proteins of Salmonella enterica. Proceedings Of The National Academy Of Sciences Of The United States Of America 1995, 92: 7252-7256. PMID: 7638176, PMCID: PMC41317, DOI: 10.1073/pnas.92.16.7252.Peer-Reviewed Original ResearchConceptsEvolutionary ratesInvasion genesInvasion proteinsCellular locationSequence identityProtein export systemNonphagocytic host cellsWarm-blooded vertebratesEnteric pathogens ShigellaSalmonella entericaS. entericaEvolutionary diversificationNiche expansionExport systemExtracellular environmentHost cellsSPA complexGenesEnteric bacteriaProteinFlagellar phaseKey eventsSubspeciesHomologuesSpa gene