2000
Human Brain β-Hydroxybutyrate and Lactate Increase in Fasting-Induced Ketosis
Pan J, Rothman D, Behar K, Stein D, Hetherington H. Human Brain β-Hydroxybutyrate and Lactate Increase in Fasting-Induced Ketosis. Cerebrovascular And Brain Metabolism Reviews 2000, 20: 1502-1507. PMID: 11043913, DOI: 10.1097/00004647-200010000-00012.Peer-Reviewed Original ResearchMeSH Keywords3-Hydroxybutyric AcidAdultBrainFastingHumansKetosisLactic AcidMagnetic Resonance SpectroscopyReference ValuesTime FactorsConceptsBHB levelsPlasma BHB levelsField magnetic resonance spectroscopyHigh-field magnetic resonance spectroscopyBrain lactateKetogenic dietCalcarine fissureNonfasted stateOccipital lobeHealthy adultsLactate increaseThird dayΒ-hydroxybutyrateKetosisBHB concentrationsBrainBHBGlucose phosphorylationLactate oxidationMagnetic resonance spectroscopy
1999
In vivo chemical shift imaging of γ‐aminobutyric acid in the human brain
Shen J, Shungu D, Rothman D. In vivo chemical shift imaging of γ‐aminobutyric acid in the human brain. Magnetic Resonance In Medicine 1999, 41: 35-42. PMID: 10025609, DOI: 10.1002/(sici)1522-2594(199901)41:1<35::aid-mrm7>3.0.co;2-c.Peer-Reviewed Original Research
1998
In vivo lactate and β‐hydroxybutyrate editing using a pure‐phase refocusing pulse train
Shen J, Novotny E, Rothman D. In vivo lactate and β‐hydroxybutyrate editing using a pure‐phase refocusing pulse train. Magnetic Resonance In Medicine 1998, 40: 783-788. PMID: 9797163, DOI: 10.1002/mrm.1910400520.Peer-Reviewed Original Research
1994
Localized 13C NMR Spectroscopy in the Human Brain of Amino Acid Labeling from d‐[1‐13C]Glucose
Gruetter R, Novotny E, Boulware S, Mason G, Rothman D, Shulman G, Prichard J, Shulman R. Localized 13C NMR Spectroscopy in the Human Brain of Amino Acid Labeling from d‐[1‐13C]Glucose. Journal Of Neurochemistry 1994, 63: 1377-1385. PMID: 7931289, DOI: 10.1046/j.1471-4159.1994.63041377.x.Peer-Reviewed Original Research
1993
Localized 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo.
Rothman D, Petroff O, Behar K, Mattson R. Localized 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo. Proceedings Of The National Academy Of Sciences Of The United States Of America 1993, 90: 5662-5666. PMID: 8516315, PMCID: PMC46781, DOI: 10.1073/pnas.90.12.5662.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidGABA concentrationGABA-transaminase inhibitor vigabatrinBrain gamma-aminobutyric acidDose-dependent elevationSeizure suppressionOccipital lobeHigh doseNonepileptic subjectsHuman volunteersHuman cortexVigabatrinDrug vigabatrinBrainPatientsHuman brainVolunteersCortexDose
1992
Localized 13C NMR spectroscopy of myo‐inositol in the human brain in vivo
Gruetter R, Rothman D, Novotny E, Hulman R. Localized 13C NMR spectroscopy of myo‐inositol in the human brain in vivo. Magnetic Resonance In Medicine 1992, 25: 204-210. PMID: 1593953, DOI: 10.1002/mrm.1910250121.Peer-Reviewed Original Research
1989
NMR Spectroscopic Investigation of the Recovery of Energy and Acid—Base Homeostasis in the Cat Brain after Prolonged Ischemia
Behar K, Rothman D, Hossmann K. NMR Spectroscopic Investigation of the Recovery of Energy and Acid—Base Homeostasis in the Cat Brain after Prolonged Ischemia. Cerebrovascular And Brain Metabolism Reviews 1989, 9: 655-665. PMID: 2777935, DOI: 10.1038/jcbfm.1989.93.Peer-Reviewed Original Research