1993
Early temporal variation of cerebral metabolites after human stroke. A proton magnetic resonance spectroscopy study.
Graham G, Blamire A, Rothman D, Brass L, Fayad P, Petroff O, Prichard J. Early temporal variation of cerebral metabolites after human stroke. A proton magnetic resonance spectroscopy study. Stroke 1993, 24: 1891-1896. PMID: 8248973, DOI: 10.1161/01.str.24.12.1891.Peer-Reviewed Original ResearchConceptsAcetyl-aspartate signalProton magnetic resonance spectroscopyCerebral infarctionProton magnetic resonance spectroscopy studyLactate signalAbundant leukocyte infiltrationAcetyl-aspartate peakNonhemorrhagic cerebral infarctionAcute cerebral infarctionDays of strokeMagnetic resonance spectroscopy studyContralateral normal brainClearance of lactateCreatine/phosphocreatineMagnetic resonance spectroscopyLong-term elevationLate deathsHuman strokeSubacute stageLeukocyte infiltrationChronic periodLesion volumeCerebral metabolitesInfarct zoneSecond examination
1992
Proton magnetic resonance spectroscopy of cerebral lactate and other metabolites in stroke patients.
Graham G, Blamire A, Howseman A, Rothman D, Fayad P, Brass L, Petroff O, Shulman R, Prichard J. Proton magnetic resonance spectroscopy of cerebral lactate and other metabolites in stroke patients. Stroke 1992, 23: 333-340. PMID: 1542892, DOI: 10.1161/01.str.23.3.333.Peer-Reviewed Original ResearchConceptsProton magnetic resonance spectroscopyStroke patientsCerebral lactateDeep cerebral infarctsElevated cerebral lactateSmall subcortical infarctsCortical stroke patientsN-acetylaspartate levelsLong-term elevationCerebral infarctsCortical strokeOngoing ischemiaSymptom onsetBrain lactateElevated lactateInitial insultSubcortical infarctsN-acetylaspartateInfarct regionLesion onsetMagnetic resonance spectroscopyInfarctsPatientsFirst weekStroke