2004
Phosphorylation of Allosteric Enzymes Can Serve Homeostasis rather than Control Flux: The Example of Glycogen Synthase
Schafer J, Fell D, Rothman D, Shulman R. Phosphorylation of Allosteric Enzymes Can Serve Homeostasis rather than Control Flux: The Example of Glycogen Synthase. 2004, 59-71. DOI: 10.1002/0470011505.ch5.Peer-Reviewed Original ResearchSummarized Reflections on Metabolism
Shulman R, Rothman D, Schafer J. Summarized Reflections on Metabolism. 2004, 175-184. DOI: 10.1002/0470011505.ch13.Peer-Reviewed Original Research
1996
Enzymatic phosphorylation of muscle glycogen synthase: a mechanism for maintenance of metabolic homeostasis.
Shulman R, Rothman D. Enzymatic phosphorylation of muscle glycogen synthase: a mechanism for maintenance of metabolic homeostasis. Proceedings Of The National Academy Of Sciences Of The United States Of America 1996, 93: 7491-7495. PMID: 8755501, PMCID: PMC38772, DOI: 10.1073/pnas.93.15.7491.Peer-Reviewed Original ResearchConceptsCovalent phosphorylationGlycogen synthaseGlycogen synthesisGlucose transportMuscle glycogen synthaseAllosteric activationMetabolic control analysisMetabolic homeostasisPhosphorylationGlycogenic fluxEnzymatic phosphorylationHexokinase stepGSaseMuscle cellsHomeostasisFractional activityMuscle glycogen synthesisSynthaseConcentrations of G6PG6P concentrationActivityEnzymeMechanismRoleHexokinase