2022
Harnessing selenocysteine to enhance microbial cell factories for hydrogen production
Patel A, Mulder D, Söll D, Krahn N. Harnessing selenocysteine to enhance microbial cell factories for hydrogen production. Frontiers In Catalysis 2022, 2: 1089176. PMID: 36844461, PMCID: PMC9961374, DOI: 10.3389/fctls.2022.1089176.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2008
Pyrrolysyl-tRNA synthetase–tRNAPyl structure reveals the molecular basis of orthogonality
Nozawa K, O’Donoghue P, Gundllapalli S, Araiso Y, Ishitani R, Umehara T, Söll D, Nureki O. Pyrrolysyl-tRNA synthetase–tRNAPyl structure reveals the molecular basis of orthogonality. Nature 2008, 457: 1163-1167. PMID: 19118381, PMCID: PMC2648862, DOI: 10.1038/nature07611.Peer-Reviewed Original ResearchConceptsAmino acidsMolecular basisLast universal common ancestorUniversal common ancestorUAG stop codonProteinogenic amino acidsCommon ancestorSuppressor tRNAStop codonDesulfitobacterium hafnienseStandard amino acidsTRNADistinct interactionsProteinPyrrolysinePylRSSelenocysteineAncestorCodonMachineryAcidVivoPairs