2022
Unconventional genetic code systems in archaea
Meng K, Chung CZ, Söll D, Krahn N. Unconventional genetic code systems in archaea. Frontiers In Microbiology 2022, 13: 1007832. PMID: 36160229, PMCID: PMC9499178, DOI: 10.3389/fmicb.2022.1007832.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGenetic code systemAmino acidsTRNA-dependent pathwayCanonical amino acidsRare amino acidArchaeal lineagesArchaeal speciesSingle lineageArchaeaMolecular mechanismsThird domainExtreme environmentsRecent discoveryLineagesBiochemical elementsHarsh conditionsEukaryotesPyrrolysineSelenocysteineOrganismsSpeciesBacteriaPathwayAcidDiscovery
1996
A mutation in protein phosphatase 2A regulatory subunit A affects auxin transport in Arabidopsis.
Garbers C, DeLong A, Deruére J, Bernasconi P, Söll D. A mutation in protein phosphatase 2A regulatory subunit A affects auxin transport in Arabidopsis. The EMBO Journal 1996, 15: 2115-2124. PMID: 8641277, PMCID: PMC450134, DOI: 10.1002/j.1460-2075.1996.tb00565.x.Peer-Reviewed Original ResearchConceptsProtein phosphatase 2AAuxin transportNaphthylphthalamic acidPhosphatase 2AProtein phosphatase 2A regulatory subunitT-DNA insertionRoot hair developmentT-DNA insertsTemperature-sensitive phenotypeRcn1 mutationROOTS CURLPhytohormone auxinArabidopsis thalianaMutant phenotypeAuxin effluxRCN1 geneRegulatory subunitHypocotyl elongationRoot branchingCell elongationShoot apexMolecular mechanismsHair developmentArabidopsisGrowth curvature
1986
Inactivation of nonsense suppressor transfer RNA genes in Schizosaccharomyces pombe Intergenic conversion and hot spots of mutation
Heyer W, Münz P, Amstutz H, Aebi R, Gysler C, Schuchert P, Szankasi P, Leupold U, Kohli J, Gamulin V, Söll D. Inactivation of nonsense suppressor transfer RNA genes in Schizosaccharomyces pombe Intergenic conversion and hot spots of mutation. Journal Of Molecular Biology 1986, 188: 343-353. PMID: 3735426, DOI: 10.1016/0022-2836(86)90159-2.Peer-Reviewed Original ResearchConceptsTRNA genesSuppressor tRNA geneIntergenic conversionDNA sequencesTransfer RNA genesYeast Schizosaccharomyces pombeSerine tRNA geneCrosses of strainsSame molecular mechanismsConcerted evolutionRNA genesProgeny sporesSchizosaccharomyces pombeAllelic conversionDifferent chromosomesConversion eventsIntron sequencesSequence transferMolecular mechanismsMutation hot spotsSpontaneous mutationsVegetative cellsGenesPoint mutationsSuppressor activity
1979
Suppression
Steege D, Söll D. Suppression. Biological Regulation And Development 1979, 433-485. DOI: 10.1007/978-1-4684-3417-0_11.Peer-Reviewed Original ResearchGenetic suppressionType phenotypeFinal gene productsWild-type phenotypePairs of genesInformational suppressorsSuppressor mutationsNonsense suppressionMissense suppressionGene productsMolecular basisFrameshift suppressionGene expressionMutant organismsMolecular mechanismsCell metabolismGenetic selectionGenetic termsMutationsSecondary mutationsTranscriptionMacromolecular componentsPrimary mutationsSuppressorPhenotype