2015
Overcoming Challenges in Engineering the Genetic Code
Lajoie M, Söll D, Church G. Overcoming Challenges in Engineering the Genetic Code. Journal Of Molecular Biology 2015, 428: 1004-1021. PMID: 26348789, PMCID: PMC4779434, DOI: 10.1016/j.jmb.2015.09.003.Peer-Reviewed Original Research
2013
UGA is an additional glycine codon in uncultured SR1 bacteria from the human microbiota
Campbell JH, O’Donoghue P, Campbell AG, Schwientek P, Sczyrba A, Woyke T, Söll D, Podar M. UGA is an additional glycine codon in uncultured SR1 bacteria from the human microbiota. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 5540-5545. PMID: 23509275, PMCID: PMC3619370, DOI: 10.1073/pnas.1303090110.Peer-Reviewed Original ResearchConceptsFrame TGA codonTGA codonGlycine codonHuman microbiotaSingle-cell genome sequencesSmall subunit rRNA sequencesComparative genomic analysisHorizontal gene transferUnique genetic codeGlycyl-tRNA synthetaseHuman Microbiome Project dataStrain-specific variationMost genesSuch taxaBisphosphate carboxylaseGenome sequenceGenetic codeGenomic analysisStriking diversityRRNA sequencesΒ-galactosidase activityGlycine residueStop codonCodonLacZ gene