2010
Murine model of chronic L. (Viannia) panamensis infection: Role of IL‐13 in disease
Castilho TM, Goldsmith‐Pestana K, Lozano C, Valderrama L, Saravia NG, McMahon‐Pratt D. Murine model of chronic L. (Viannia) panamensis infection: Role of IL‐13 in disease. European Journal Of Immunology 2010, 40: 2816-2829. PMID: 20827674, PMCID: PMC3289133, DOI: 10.1002/eji.201040384.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnimalsChronic DiseaseDisease Models, AnimalEnzyme-Linked Immunosorbent AssayFemaleHumansInterferon-gammaInterleukin-13LeishmaniaLeishmaniasis, CutaneousMaleMiceMice, Inbred BALB CMice, KnockoutMiddle AgedReceptors, Interleukin-4Th1 CellsTh2 CellsTumor Necrosis Factor-alphaYoung AdultConceptsL. panamensis infectionsIL-13Panamensis infectionChronic diseasesImmunodeficient miceMurine modelMixed Th1/Th2 responseBALB/c mouse modelTh1/Th2 responsePrevalent etiologic agentHuman cutaneous leishmaniasisPresence of TNFPrevention of leishmaniasisIL-17Immunological mechanismsTh2 responsesIL-10Recurrent lesionsChronic infectionEvident lesionsMice resemblesT cellsImmune responsePersistent infectionLeishmania organisms
1987
Serodiagnostic assay for visceral leishmaniasis employing monoclonal antibodies
Jaffe C, McMahon-Pratt D. Serodiagnostic assay for visceral leishmaniasis employing monoclonal antibodies. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 1987, 81: 587-594. PMID: 3445339, DOI: 10.1016/0035-9203(87)90418-4.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalAntigen-Antibody ReactionsAntigens, ProtozoanBinding, CompetitiveEnzyme-Linked Immunosorbent AssayHumansLeishmaniasis, VisceralSpecies SpecificityConceptsVisceral leishmaniasisMonoclonal antibodiesSerodiagnostic assaysVL seraParasite antigensChagas diseaseSystemic lupus erythematosusNon-endemic areasDifferent parasite antigensLeishmania antigenLupus erythematosusMucocutaneous leishmaniasisLepromatous leprosyNegative control seraPositive casesSpecies-specific monoclonal antibodiesNormal serumControl seraRapid diagnosisAntigenSerum dilutionSerumAntibodiesLeishmaniasisSpecific inhibition