2023
Megahertz Sampling of Prestin (SLC26a5) Voltage-Sensor Charge Movements in Outer Hair Cell Membranes Reveals Ultrasonic Activity that May Support Electromotility and Cochlear Amplification
Santos-Sacchi J, Bai J, Navaratnam D. Megahertz Sampling of Prestin (SLC26a5) Voltage-Sensor Charge Movements in Outer Hair Cell Membranes Reveals Ultrasonic Activity that May Support Electromotility and Cochlear Amplification. Journal Of Neuroscience 2023, 43: 2460-2468. PMID: 36868859, PMCID: PMC10082455, DOI: 10.1523/jneurosci.2033-22.2023.Peer-Reviewed Original ResearchConceptsConformational switchingMammalian hearingMembrane motor proteinCochlear amplificationMotor protein prestinVoltage-sensor charge movementOuter hair cell electromotilityHair cell electromotilityProtein prestinMotor proteinsConformation switchingCharge movementPrestinPrestin activityCell membraneOHC electromotilityHair cell membraneElectromotilityTransmembrane voltageOrgan of CortiAmplificationMammalsMembrane capacitanceProtein
2006
Hair Cells – Beyond the Transducer
Housley GD, Marcotti W, Navaratnam D, Yamoah EN. Hair Cells – Beyond the Transducer. The Journal Of Membrane Biology 2006, 209: 89. PMID: 16773496, DOI: 10.1007/s00232-005-0835-7.BooksConceptsHair cell developmentHair cellsHair cell physiologySensory hair cellsOuter hair cell electromotilityMolecular physiologyHair cell electromotilityCell physiologyCell developmentPhysiological functionsMechanoelectrical transductionIon channelsBiophysical statusCell functionTransductionNeurotransmitter releaseHair cell functionPhysiologyCellsConsiderable arrayBroad dynamic rangeReview seriesMembrane conductanceElectromotilityPathway