2023
Dysregulation of the endogenous cannabinoid system following opioid exposure
Mohammad Aghaei A, Saali A, Canas M, Weleff J, D'Souza D, Angarita G, Bassir Nia A. Dysregulation of the endogenous cannabinoid system following opioid exposure. Psychiatry Research 2023, 330: 115586. PMID: 37931479, PMCID: PMC10842415, DOI: 10.1016/j.psychres.2023.115586.Peer-Reviewed Original ResearchConceptsEndocannabinoid systemECS componentsBrain regionsNovel neurobiological targetsTreatment of OUDEndogenous opioid systemOpioid-related deathsEndogenous cannabinoid systemSpecific brain regionsECS dysregulationOpioid exposureOUD treatmentOpioid systemCannabinoid systemNeurobiological targetsNew medicationsPreclinical literatureCannabinoid receptorsEndogenous ligandTherapeutic potentialStudy typePresent potential targetsExposure protocolOpioidsPreclinical research
2009
Cannabinoids and psychosis
Sewell RA, Ranganathan M, D'Souza DC. Cannabinoids and psychosis. International Review Of Psychiatry 2009, 21: 152-162. PMID: 19367509, DOI: 10.1080/09540260902782802.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCannabinoidsCannabisHumansMarijuana AbuseMarijuana SmokingPsychotic DisordersReceptors, CannabinoidRisk FactorsSchizophreniaConceptsGeneral populationPsychotic disordersTrigger relapseCannabis usersCognitive symptomsCross-sectional studyIndividual vulnerabilityCannabis useCannabinoid receptor functionLongitudinal studyCase seriesPsychotic illnessPsychotic symptomsCannabisHealthy individualsSchizophreniaPharmacological studiesReceptor functionAutobiographical accountsPsychosisEarly exposureSymptomsTwo-fold increaseConsiderable evidenceComponent causes
2006
The acute effects of cannabinoids on memory in humans: a review
Ranganathan M, D’Souza D. The acute effects of cannabinoids on memory in humans: a review. Psychopharmacology 2006, 188: 425-444. PMID: 17019571, DOI: 10.1007/s00213-006-0508-y.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCannabinoidsCannabisDrug ToleranceHumansMarijuana AbuseMemoryReceptors, CannabinoidSubstance Withdrawal SyndromeConceptsStages of memoryHuman literatureDelay-dependent mannerIntrusion errorsMemory taskFree recallPsychological testsAmnestic effectsCognitive functionConstituent cannabinoidsRobust effectMemoryPreclinical literatureFuture researchResultsAcute administrationNeurochemical basisEffects of cannabinoidsDrug useExogenous cannabinoidsIssues of doseAcute effectsLarge bodyLong-term potentiationSmall sample sizeRationaleCannabis
2001
Cannabinoid Antagonists: A Treatment in Search of an Illness
D'Souza D, Kosten T. Cannabinoid Antagonists: A Treatment in Search of an Illness. JAMA Psychiatry 2001, 58: 330-331. PMID: 11296092, DOI: 10.1001/archpsyc.58.4.330.Peer-Reviewed Original Research