2016
Direct vitamin D3 actions on rhesus macaque follicles in three-dimensional culture: assessment of follicle survival, growth, steroid, and antimüllerian hormone production
Xu J, Hennebold JD, Seifer DB. Direct vitamin D3 actions on rhesus macaque follicles in three-dimensional culture: assessment of follicle survival, growth, steroid, and antimüllerian hormone production. Fertility And Sterility 2016, 106: 1815-1820.e1. PMID: 27678030, PMCID: PMC5136302, DOI: 10.1016/j.fertnstert.2016.08.037.Peer-Reviewed Original ResearchConceptsVitamin D3Follicle survivalPreantral follicle survivalAntral folliclesWeek 5High-dose vitamin D3Direct actionAntimüllerian hormone concentrationsAntral follicle diameterPrimate follicular developmentVitamin D3 actionAntral follicle growthDihydroxy vitamin D3Rhesus monkey ovariesSecondary preantral folliclesFemale rhesus macaquesMacaque folliclesPrimate follicleD3 actionAMH concentrationsNational Primate Research CenterAMH productionPrimate Research CenterFollicle diameterMAIN OUTCOME
1998
Effects of ovarian source, patient age, and menstrual cycle phase on in vitro maturation of immature human oocytes
Whitacre K, Seifer D, Friedman C, Coskun S, Kennard E, Kim M, Alak B. Effects of ovarian source, patient age, and menstrual cycle phase on in vitro maturation of immature human oocytes. Fertility And Sterility 1998, 70: 1015-1021. PMID: 9848288, DOI: 10.1016/s0015-0282(98)00339-2.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgingCell CycleCell NucleusCells, CulturedCellular SenescenceFemaleFertilization in VitroHumansMenstrual CycleOocytesOvaryConceptsGerminal vesicle breakdownOvarian sourceNuclear maturationPatient ageGynecologic surgeryFollicular phaseLuteal phaseImmature human oocytesFinal meiotic maturationMenstrual cycle phaseYears of agePercentage of oocytesCycle phaseMetaphase II stageIVF programMenstrual cyclePatient criteriaMAIN OUTCOMEVitro maturationPatientsHuman oocytesOocyte maturationMII stageOocyte's abilityVesicle breakdownActivin a stimulates meiotic maturation of human oocytes and modulates granulosa cell steroidogenesis in vitro
Alak B, Coskun S, Friedman C, Kennard E, Kim M, Seifer D. Activin a stimulates meiotic maturation of human oocytes and modulates granulosa cell steroidogenesis in vitro. Fertility And Sterility 1998, 70: 1126-1130. PMID: 9848305, DOI: 10.1016/s0015-0282(98)00386-0.Peer-Reviewed Original ResearchConceptsGranulosa cell steroidogenesisGerminal vesicle breakdownGranulosa cellsActivin AE2 secretionSteroid secretionCell steroidogenesisNonluteinized granulosa cellsMeiotic maturationMetaphase IIUniversity Medical CenterAntral granulosa cellsNonovarian pathologyInhibin AMedical CenterMAIN OUTCOMEActivin A.Oocyte meiotic maturationImmature oocytesHuman oocytesOocyte maturationSecretionVesicle breakdownProgesteroneSteroidogenesis
1996
Differential secretion of dimeric inhibin in cultured luteinized granulosa cells as a function of ovarian reserve
Seifer DB, Gardiner AC, Lambert-Messerlian G, Schneyer AL. Differential secretion of dimeric inhibin in cultured luteinized granulosa cells as a function of ovarian reserve. The Journal Of Clinical Endocrinology & Metabolism 1996, 81: 736-739. PMID: 8636296, DOI: 10.1210/jcem.81.2.8636296.Peer-Reviewed Original ResearchConceptsDay 3 serum FSHLuteinized granulosa cellsHigh FSH groupDimeric inhibinSerum FSHFSH groupPg/Granulosa cellsFSH levelsOvarian reserveOvulation inductionProgesterone concentrationsDay 3 serum FSH levelsCultured luteinized granulosa cellsDimeric inhibin productionLow FSH groupSerum FSH levelsFertilization-embryo transferHigher FSH levelsReproductive technology programGranulosa cell levelTotal inhibinInhibin concentrationsInhibin productionProspective study
1995
Assessment of sex chromosome composition using fluorescent in situ hybridization as an adjunct to GTG-banding.
Mark HF, Meyers-Seifer CH, Seifer DB, Demoranville BM, Jackson IM. Assessment of sex chromosome composition using fluorescent in situ hybridization as an adjunct to GTG-banding. Annals Of Clinical & Laboratory Science 1995, 25: 402-8. PMID: 7486815.Peer-Reviewed Original Research