Heparin-Induced Thrombocytopenia and Thrombosis: Detection and Specificity of a Platelet-Aggregating IgG
Sandler R, Seifer D, Morgan K, Pockros P, Wypych J, Weiss L, Schiffman S. Heparin-Induced Thrombocytopenia and Thrombosis: Detection and Specificity of a Platelet-Aggregating IgG. American Journal Of Clinical Pathology 1985, 83: 760-764. PMID: 4003343, DOI: 10.1093/ajcp/83.6.760.Peer-Reviewed Original ResearchMeSH KeywordsBlood Coagulation FactorsChromatography, AffinityFemaleHeparinHumansImmunoglobulin GMiddle AgedPlatelet Activating FactorPlatelet AggregationSepharoseThrombocytopeniaThrombosisConceptsMultiple arterial occlusionsResult of thrombocytopeniaHeparin-Induced ThrombocytopeniaSamples of serumPlatelet-aggregating factorCatastrophic syndromeWorst sequelaeAntithrombotic therapyHeparin therapyArterial occlusionArterial thrombosisIgG productionPresence of heparinNormal plateletsPlasma samplesHeparinThrombocytopeniaFurther studiesThrombosisTherapyIgGSequelaeSepticemiaSyndrome