2019
Photodynamic therapy for cutaneous squamous cell carcinoma in situ: Impact of anatomic location, tumor diameter, and incubation time on effectiveness
Kibbi N, Zhang Y, Leffell DJ, Christensen SR. Photodynamic therapy for cutaneous squamous cell carcinoma in situ: Impact of anatomic location, tumor diameter, and incubation time on effectiveness. Journal Of The American Academy Of Dermatology 2019, 82: 1124-1130. PMID: 31712171, DOI: 10.1016/j.jaad.2019.10.079.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAminolevulinic AcidAnalysis of VarianceBiopsy, NeedleCarcinoma in SituCarcinoma, Squamous CellCohort StudiesDisease-Free SurvivalFemaleHumansImmunohistochemistryLogistic ModelsMaleMiddle AgedMultivariate AnalysisNeoplasm InvasivenessNeoplasm StagingPhotochemotherapyPrognosisRetrospective StudiesSkin NeoplasmsSurvival AnalysisTreatment OutcomeTumor BurdenConceptsCutaneous squamous cell carcinomaALA incubation timeSquamous cell carcinomaTumor diameterALA-PDTSubsequent recurrenceCell carcinomaAnatomic locationInitial complete response ratePhotodynamic therapyCases of SCCISMultivariate analysis factorsComplete response rateMedical record reviewEffectiveness of PDTPatient demographicsClinical responseMedian timeRetrospective reviewRecord reviewRetrospective studyTreatment detailsSingle institutionEffective treatmentResponse rate
2015
Melanoma in situ Part I. Epidemiology, screening, and clinical features
Higgins HW, Lee KC, Galan A, Leffell DJ. Melanoma in situ Part I. Epidemiology, screening, and clinical features. Journal Of The American Academy Of Dermatology 2015, 73: 181-190. PMID: 26183967, DOI: 10.1016/j.jaad.2015.04.014.Peer-Reviewed Original ResearchConceptsClinical featuresPart I. EpidemiologyReview of melanomaUnderstanding of melanomaIncidence of melanomaMedical education articleI. EpidemiologyClinical outcomesTreatment optionsClinical managementRisk factorsMalignant melanomaBiologic behaviorClinical studiesMelanomaEpidemiologyIncidenceHigh percentageEducation articlesHistopathologyPathologyMelanoma in situ Part II. Histopathology, treatment, and clinical management
Higgins HW, Lee KC, Galan A, Leffell DJ. Melanoma in situ Part II. Histopathology, treatment, and clinical management. Journal Of The American Academy Of Dermatology 2015, 73: 193-203. PMID: 26183968, DOI: 10.1016/j.jaad.2015.03.057.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, TopicalAminoquinolinesBiopsy, NeedleCarcinoma in SituFemaleHumansImiquimodImmunohistochemistryImmunotherapyInjections, IntralesionalInterferon-alphaLaser TherapyMaleMelanomaMohs SurgeryNeoplasm InvasivenessNeoplasm StagingPrognosisRandomized Controlled Trials as TopicSkin NeoplasmsTreatment Outcome
1999
Status of residual tumor in patients with squamous cell carcinoma referred for Mohs micrographic surgery.
McGovern T, Grossman D, Fitzgerald D, Glusac E, Leffell D. Status of residual tumor in patients with squamous cell carcinoma referred for Mohs micrographic surgery. JAMA Dermatology 1999, 135: 1557-9. PMID: 10606080, DOI: 10.1001/archderm.135.12.1557.Peer-Reviewed Original Research