Characterization of pain and somatization and its relationship with psychopathology in early onset psychosis
van der Heijden H, Goldman M, Ray A, Golden E, Petty C, Deaso E, Hojlo M, Sethna N, Glahn D, Gonzalez-Heydrich J, Upadhyay J. Characterization of pain and somatization and its relationship with psychopathology in early onset psychosis. Journal Of Psychiatric Research 2024, 179: 77-82. PMID: 39260111, PMCID: PMC11531992, DOI: 10.1016/j.jpsychires.2024.09.006.Peer-Reviewed Original ResearchBrief Psychiatric Rating ScaleEarly onset psychosisDegree of psychopathologyBrief Psychiatric Rating Scale totalBrief Psychiatric Rating Scale subscalesDimensions of psychopathologyPsychiatric Rating ScaleChlorpromazine equivalent doseAntipsychotic medication usageControl of psychosisStructured Clinical InterviewAdult-onset psychosisPain catastrophizingSelf-report questionnairesCentral sensitizationPain severityFrequent cause of distressClinical interviewSomatic severityClinical presentation of painSomatic symptomsPsychopathologyPsychosisSubscale scoresRating ScaleRelating depressive and manic symptomatology to 1H-MRS spectra
Choquette A, Dager A, Marjańska M, Zatony M, Pearlson G, Glahn D, Knowles E. Relating depressive and manic symptomatology to 1H-MRS spectra. Journal Of Affective Disorders Reports 2024, 16: 100774. DOI: 10.1016/j.jadr.2024.100774.Peer-Reviewed Original ResearchAnterior cingulate cortexN-acetylaspartateRight anterior cingulate cortexAssociated with maniaDepressive symptom scalesSymptom Rating ScaleProfiles of associationDisorder symptomatologyManic symptomsReduced N-acetylaspartateCingulate cortexAffective disordersNeurochemical levelsSymptom ScaleManiaCholine-containing compoundsDichotomous diagnosisMagnetic resonance spectroscopyRating ScalePotential in vivo biomarkersHippocampusIllness etiologyMagnetic resonance spectroscopy dataTotal cholineFollow-up