Amplification and overexpression of E2 ubiquitin conjugase UBE2T promotes homologous recombination in multiple myeloma.
Alagpulinsa D, Kumar S, Talluri S, Nanjappa P, Buon L, Chakraborty C, Samur M, Szalat R, Shammas M, Munshi N. Amplification and overexpression of E2 ubiquitin conjugase UBE2T promotes homologous recombination in multiple myeloma. Blood Advances 2019, 3: 3968-3972. PMID: 31805191, PMCID: PMC6963244, DOI: 10.1182/bloodadvances.2019000181.Peer-Reviewed Original ResearchConceptsMultiple myeloma cellsMyeloma cellsUBE2TPotential therapeutic targetMultiple myelomaTherapeutic targetCellsMyelomaChemosensitivityHomologous recombination activity