Dan Doyle
Postdoctoral Fellow in the Child Study CenterAbout
Research
Publications
2026
Competing programs shape cortical sensorimotor–association axis development
Tsyporin J, Zhang M, Qi C, Segal A, Li X, Kim H, Choi S, Pavlovic I, Bandiera S, Finn T, Kim S, Shibata A, Nakamura T, Onishi K, Zhang Z, Hammarlund E, Su G, Salla N, Kachko J, Hawley C, Li S, Doyle D, Peng X, Nottoli T, Ruiz-Reig N, Tissir F, Nakagawa Y, Herzog E, Ma S, Pattabiraman K, Shimogori T, Duque A, Fornito A, Huang H, Shibata M, Chen B, Sestan N. Competing programs shape cortical sensorimotor–association axis development. Nature 2026, 656: 688-699. PMID: 42386980, PMCID: PMC13489954, DOI: 10.1038/s41586-026-10699-x.Peer-Reviewed Original Research
2025
Unique and divergent features of human brain development
Salamon I, Doyle D, Bandler R, Pattabiraman K, Sestan N. Unique and divergent features of human brain development. Current Opinion In Neurobiology 2025, 95: 103133. PMID: 41187489, PMCID: PMC12626412, DOI: 10.1016/j.conb.2025.103133.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2022
Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity
Funk O, Qalieh Y, Doyle D, Lam M, Kwan K. Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2116956119. PMID: 35930666, PMCID: PMC9371731, DOI: 10.1073/pnas.2116956119.Peer-Reviewed Original ResearchNeurogenic–angiogenic synchrony via lactate
Doyle D, Kwan K. Neurogenic–angiogenic synchrony via lactate. Nature Neuroscience 2022, 25: 839-840. PMID: 35788196, DOI: 10.1038/s41593-022-01111-8.Peer-Reviewed Original Research
2021
Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity
Doyle D, Lam M, Qalieh A, Qalieh Y, Sorel A, Funk O, Kwan K. Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity. Proceedings Of The National Academy Of Sciences Of The United States Of America 2021, 118: e2100686118. PMID: 34011608, PMCID: PMC8166177, DOI: 10.1073/pnas.2100686118.Peer-Reviewed Original ResearchAbnormalities, MultipleAnimalsCerebral CortexChromatinConnectomeCorpus CallosumDNA-Binding ProteinsFaceGene DeletionGene Expression RegulationGray MatterHand Deformities, CongenitalHumansIntellectual DisabilityLoss of Function MutationMiceMice, TransgenicMicrognathismNeckNeural PathwaysNeuronsThalamusTranscription FactorsVibrissaeWhite Matter
2020
Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
Keil J, Doyle D, Qalieh A, Lam M, Funk O, Qalieh Y, Shi L, Mohan N, Sorel A, Kwan K. Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80. Nature Communications 2020, 11: 3839. PMID: 32737294, PMCID: PMC7395731, DOI: 10.1038/s41467-020-17551-4.Peer-Reviewed Original ResearchAnimalsApoptosisATPases Associated with Diverse Cellular ActivitiesBRCA2 ProteinCell DivisionChromatinChromatin Assembly and DisassemblyDNADNA Breaks, Double-StrandedDNA-Binding ProteinsEmbryo, MammalianGene Expression Regulation, DevelopmentalMiceMice, TransgenicNeocortexNeural Stem CellsNeurogenesisRecombinational DNA RepairSignal TransductionTumor Suppressor Protein p53YY1 Transcription Factor
Academic Achievements & Community Involvement
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Pattabiraman and Sestan Labs
Lab
100 College Street
New Haven, CT 06510