2006
Proteome analysis of mitochondrial outer membrane from Neurospora crassa
Schmitt S, Prokisch H, Schlunck T, Camp DG, Ahting U, Waizenegger T, Scharfe C, Meitinger T, Imhof A, Neupert W, Oefner PJ, Rapaport D. Proteome analysis of mitochondrial outer membrane from Neurospora crassa. Proteomics 2006, 6: 72-80. PMID: 16294304, DOI: 10.1002/pmic.200402084.Peer-Reviewed Original ResearchConceptsMitochondrial outer membraneOuter membraneOuter membrane vesiclesNeurospora crassaImport machineryEukaryotic cellsGenetic systemOMV proteinsBiosynthetic pathwayProteomic studiesNovel functionProteome analysisIntracellular locationMembrane vesiclesTryptic peptide digestsProteinCrassaNumerous interactionsGel electrophoresisPeptide digestsLC-MS/MSMembraneProteomeOrganellesMitochondria
2004
Integrative Analysis of the Mitochondrial Proteome in Yeast
Prokisch H, Scharfe C, Camp DG, Xiao W, David L, Andreoli C, Monroe ME, Moore RJ, Gritsenko MA, Kozany C, Hixson KK, Mottaz HM, Zischka H, Ueffing M, Herman ZS, Davis RW, Meitinger T, Oefner PJ, Smith RD, Steinmetz LM. Integrative Analysis of the Mitochondrial Proteome in Yeast. PLOS Biology 2004, 2: e160. PMID: 15208715, PMCID: PMC423137, DOI: 10.1371/journal.pbio.0020160.Peer-Reviewed Original ResearchConceptsMitochondrial proteomeGenomic approachesPhenotype screeningGenome-wide approachesSubcellular localization studiesComplex mitochondrial disordersDifferent genomic approachesProtein interaction analysisYeast mitochondriaMitochondrial proteinsMitochondrial organellesProteomic approachProteome studiesAbundant proteinsExpression analysisCandidate genesExpression profilingIntegrative analysisMitochondrial functionLocalization studiesOrganellesMitochondrial disordersProteinSystematic identificationMass spectrometry