Timing of Newborn Blood Collection Alters Metabolic Disease Screening Performance
Peng G, Tang Y, Cowan TM, Zhao H, Scharfe C. Timing of Newborn Blood Collection Alters Metabolic Disease Screening Performance. Frontiers In Pediatrics 2021, 8: 623184. PMID: 33553077, PMCID: PMC7854909, DOI: 10.3389/fped.2020.623184.Peer-Reviewed Original ResearchCarnitine transport defectBlood collectionMethylmalonic acidemiaIsovaleric acidemiaMarker levelsMetabolic disordersElevated marker levelsMetabolic marker levelsFalse-positive casesInborn metabolic disordersNewborn screening dataGestational ageClinical variablesBirth weightStandard groupFalse positive rateMetabolic changesDisease screeningHigh false positive rateEffect size analysisPhenylketonuriaScreening performanceAcidemiaCollection groupDisorders