RbAp48 Is a Critical Mediator Controlling the Transforming Activity of Human Papillomavirus Type 16 in Cervical Cancer*
Kong L, Yu X, Bai X, Zhang W, Zhang Y, Zhao W, Jia J, Tang W, Zhou Y, Liu C. RbAp48 Is a Critical Mediator Controlling the Transforming Activity of Human Papillomavirus Type 16 in Cervical Cancer*. Journal Of Biological Chemistry 2007, 282: 26381-26391. PMID: 17616526, DOI: 10.1074/jbc.m702195200.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarrier ProteinsCaspase 3Caspase 8Cell Line, TransformedCell Line, TumorCell Transformation, ViralCellular SenescenceCyclin DCyclinsElectrophoresis, Gel, Two-DimensionalFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticHeLa CellsHuman papillomavirus 16HumansMiceMice, NudeNeoplasm TransplantationNuclear ProteinsOncogene Proteins, ViralPapillomavirus E7 ProteinsPhenotypeProto-Oncogene Proteins c-mycRepressor ProteinsRetinoblastoma ProteinRetinoblastoma-Binding Protein 4RNA, Small InterferingTumor Suppressor Protein p53Uterine Cervical DysplasiaUterine Cervical NeoplasmsConceptsCervical cancerH8 cellsCyclin D1Critical mediatorHuman papillomavirus infectionCervical cancer CaSki cellsTumor formationCervical cancer-derived cell linesCervical intraepithelial neoplasiaHuman papillomavirus type 16Papillomavirus type 16Cancer-derived cell linesSenescence-like phenotypePapillomavirus infectionIntraepithelial neoplasiaEnzyme caspase-3Cervical carcinogenesisType 16Nude miceCaSki cellsCancerTumor suppressor retinoblastomaOncogenic genesProtein 4Cell proliferationThe Retinoblastoma Protein Is an Essential Mediator of Osteogenesis That Links the p204 Protein to the Cbfa1 Transcription Factor Thereby Increasing Its Activity*
Luan Y, Yu XP, Xu K, Ding B, Yu J, Huang Y, Yang N, Lengyel P, Di Cesare PE, Liu CJ. The Retinoblastoma Protein Is an Essential Mediator of Osteogenesis That Links the p204 Protein to the Cbfa1 Transcription Factor Thereby Increasing Its Activity*. Journal Of Biological Chemistry 2007, 282: 16860-16870. PMID: 17439944, DOI: 10.1074/jbc.m610943200.Peer-Reviewed Original ResearchConceptsGene activationTranscription factorsRetinoblastoma proteinProtein-protein interactionsChromatin immunoprecipitation assaysMesenchymal cell lineSkeletal muscle myotubesP204 expressionP204 proteinCore-binding factor alpha1Numerous proteinsImmunoprecipitation assaysSuch mutantsOsteocalcin geneReporter geneGene expressionAntisense RNAMuscle myotubesOsteoblast differentiationCbfa1Factor alpha1ProteinEssential mediatorTernary complexCell lines