2021
Clinical Laboratory Biosafety Gaps: Lessons Learned from Past Outbreaks Reveal a Path to a Safer Future
Cornish NE, Anderson NL, Arambula DG, Arduino MJ, Bryan A, Burton NC, Chen B, Dickson BA, Giri JG, Griffith NK, Pentella MA, Salerno RM, Sandhu P, Snyder JW, Tormey CA, Wagar EA, Weirich EG, Campbell S. Clinical Laboratory Biosafety Gaps: Lessons Learned from Past Outbreaks Reveal a Path to a Safer Future. Clinical Microbiology Reviews 2021, 34: 10.1128/cmr.00126-18. PMID: 34105993, PMCID: PMC8262806, DOI: 10.1128/cmr.00126-18.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsClinical laboratoriesPatient specimensPersonal protective equipmentHospital clinical laboratoriesPatient deathInfectious disease outbreaksInfectious agentsReliable laboratory testingBiocontainment unitPatient careTest utilizationOngoing outbreakProtective equipmentClinical laboratory professionalsAnatomic pathologySpecimen collectionEbola outbreakPublic healthLaboratory professionalsImportance of biosafetyPast outbreaksOutbreakLaboratory testingDisease outbreaksCompetency assessment
2015
Computational Approach to Annotating Variants of Unknown Significance in Clinical Next Generation Sequencing
Schulz WL, Tormey CA, Torres R. Computational Approach to Annotating Variants of Unknown Significance in Clinical Next Generation Sequencing. Lab Medicine 2015, 46: 285-289. PMID: 26489672, DOI: 10.1309/lmwzh57brwopr5rq.Peer-Reviewed Original ResearchConceptsNext-generation sequencingClinical significanceUnknown clinical significanceMalignant neoplasmsHematologic malignanciesClinical next-generation sequencingSoftware algorithmsGeneration sequencingUnknown significanceBenign variantsConflicting resultsClinical laboratoriesComputational toolsCommon technologyAlgorithm