1999
Early expression of marker genes in the rabbit medial collateral and anterior cruciate ligaments: The use of different viral vectors and the effects of injury
Hildebrand K, Deie M, Allen C, Smith D, Georgescu H, Evans C, Robbins P, Woo S. Early expression of marker genes in the rabbit medial collateral and anterior cruciate ligaments: The use of different viral vectors and the effects of injury. Journal Of Orthopaedic Research® 1999, 17: 37-42. PMID: 10073645, DOI: 10.1002/jor.1100170107.Peer-Reviewed Original ResearchConceptsAnterior cruciate ligamentMedial collateral ligamentCruciate ligamentCollateral ligamentMedial collateralKnee ligamentsBilateral knee surgeryLigament fibroblastsVivo techniquesAnterior cruciate ligament fibroblastsEffects of injuryEx vivo techniquesKnee surgeryLeft kneeRight kneeLacZ marker geneGroup 2Group 1Cytokine deliveryGroup 3Ligament samplesDifferent viral vectorsLigamentGene expressionWeeks
1997
The effects of age on rabbit MCL fibroblast matrix synthesis in response to TGF-β1 or EGF
Deie M, Marui T, Allen C, Hildebrand K, Georgescu H, Niyibizi C, Woo S. The effects of age on rabbit MCL fibroblast matrix synthesis in response to TGF-β1 or EGF. Mechanisms Of Ageing And Development 1997, 97: 121-130. PMID: 9226631, DOI: 10.1016/s0047-6374(97)00049-3.Peer-Reviewed Original ResearchMeSH KeywordsAgingAnimalsCells, CulturedCollagenDose-Response Relationship, DrugEpidermal Growth FactorFibroblastsMedial Collateral Ligament, KneeProtein BiosynthesisRabbitsTransforming Growth Factor betaConceptsMedial collateral ligamentEffect of ageEpidermal growth factorTotal protein synthesisMCL fibroblastsGrowth factorImmature rabbitsProtein synthesisSenescent groupCollateral ligamentTGF-β1Baseline levelsOwn controlDifferent dosesLigament fibroblastsLess collagenCollagen synthesisEGF doseRabbitsAgeSignificant reductionDoseDosesMatrix synthesisFibroblasts