2011
The RNA Interference Pathway in Trypanosoma brucei
Ullu E, Kolev N, Barnes R, Tschudi C. The RNA Interference Pathway in Trypanosoma brucei. Nucleic Acids And Molecular Biology 2011, 28: 167-185. DOI: 10.1007/978-3-642-28687-2_8.Peer-Reviewed Original ResearchRNA interference (RNAi) pathwayInterference pathwayEarly divergent eukaryoteMost eukaryotic cellsSequence-specific mannerEukaryotic evolutionDivergent eukaryotesHigher eukaryotesRNAi machineryEukaryotic cellsLong dsRNAsRNAi mechanismTarget transcriptsTrypanosoma bruceiConsequence cellsSpecific defense mechanismsEukaryotesProtozoan parasiteDefense mechanismsTranscriptsCurrent understandingNucleic acidsPathwayHighlight similaritiesSuch mechanisms
2001
Unusual diversity in α-amanitin sensitivity of RNA polymerases in trichomonads
Vaňáčová Š, Tachezy J, Ullu E, Tschudi C. Unusual diversity in α-amanitin sensitivity of RNA polymerases in trichomonads. Molecular And Biochemical Parasitology 2001, 115: 239-247. PMID: 11420110, DOI: 10.1016/s0166-6851(01)00294-8.Peer-Reviewed Original ResearchConceptsUnusual diversityResistant RNA polymerase IIProtein coding genesParasitic protist Trichomonas vaginalisRNA polymerase IIAlpha-amanitin sensitivityProtist Trichomonas vaginalisGenus-specific patternsTritrichomonas foetusLysolecithin-permeabilized cellsUnicellular eukaryotesCoding genesPolymerase IIRNAP IIRNAP IIIRNA polymeraseTrichomonad speciesAlpha-amanitinT. vaginalisRNA synthesisΑ-amanitin sensitivityDiversityTrichomonadsRelated groupsEukaryotes
2000
Cotranscriptional Cap 4 Formation on the Trypanosoma brucei Spliced Leader RNA*
Mair G, Ullu E, Tschudi C. Cotranscriptional Cap 4 Formation on the Trypanosoma brucei Spliced Leader RNA*. Journal Of Biological Chemistry 2000, 275: 28994-28999. PMID: 10880518, DOI: 10.1074/jbc.m004193200.Peer-Reviewed Original ResearchConceptsCap 4 structureSL RNAMRNA cap formationT. brucei cellsSpliced leader RNARNA cap structureSpliced leader sequenceTranscriptional arrestTrypanosomatid protozoaBrucei cellsLeader RNACap 4Cotranscriptional mechanismLeader sequenceTrypanosoma bruceiCap structureRNA transcriptsRibonucleoprotein formationAdenosine residuesPosition 117RNATranscriptsCap formationNucleotidesEukaryotes