Tissue Microarray Analysis of 560 Patients with Colorectal Adenocarcinoma: High Expression of HuR Predicts Poor Survival
Yoo PS, Sullivan CA, Kiang S, Gao W, Uchio EM, Chung GG, Cha CH. Tissue Microarray Analysis of 560 Patients with Colorectal Adenocarcinoma: High Expression of HuR Predicts Poor Survival. Annals Of Surgical Oncology 2009, 16: 200. PMID: 19009247, DOI: 10.1245/s10434-008-0209-3.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAgedAged, 80 and overAntigens, SurfaceAutomationBiomarkers, TumorColorectal NeoplasmsELAV ProteinsELAV-Like Protein 1FemaleFollow-Up StudiesHumansImage Processing, Computer-AssistedImmunoenzyme TechniquesMaleMiddle AgedNeoplasm StagingPlatelet Endothelial Cell Adhesion Molecule-1PrognosisRNA-Binding ProteinsSurvival RateTissue Array AnalysisVascular Endothelial Growth Factor AYoung AdultConceptsVascular endothelial growth factorColorectal adenocarcinomaPoor survivalHuR expressionKaplan-Meier analysisNovel therapeutic targetTissue microarray analysisEndothelial growth factorChi-squared testInstitutional review boardHuR protein expressionAdvanced diseaseClinical outcomesHighest quartileIndependent predictorsPrognostic significanceColorectal cancerCox regressionTumor stageMetastasis stageColorectal carcinomaLowest quartileClinical dataExpression of HuRTissue microarray