2010
PMCA2 regulates apoptosis during mammary gland involution and predicts outcome in breast cancer
VanHouten J, Sullivan C, Bazinet C, Ryoo T, Camp R, Rimm DL, Chung G, Wysolmerski J. PMCA2 regulates apoptosis during mammary gland involution and predicts outcome in breast cancer. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 11405-11410. PMID: 20534448, PMCID: PMC2895115, DOI: 10.1073/pnas.0911186107.Peer-Reviewed Original ResearchConceptsPMCA2 expressionBreast cancerT47D breast cancer cellsIntracellular calcium levelsBreast cancer progressionBreast cancer cellsEpithelial cell apoptosisPoor outcomeIntracellular calciumCalcium levelsMammary gland involutionCancer progressionCell apoptosisCancer cellsMammary involutionApoptosisGland involutionCancerMammary epithelial cell apoptosisOutcomesPMCA2Triggers apoptosisApical surfaceExpressionOverexpression
2008
Biomarker Validation: In Situ Analysis of Protein Expression Using Semiquantitative Immunohistochemistry-Based Techniques
Sullivan CA, Chung GG. Biomarker Validation: In Situ Analysis of Protein Expression Using Semiquantitative Immunohistochemistry-Based Techniques. Clinical Colorectal Cancer 2008, 7: 172-177. PMID: 18621634, DOI: 10.3816/ccc.2008.n.022.Peer-Reviewed Original ResearchConceptsProteomic high-throughput technologiesProtein expressionExpression profile dataHigh-throughput technologiesDrug development targetsMicroarray technologyImmunohistochemistry-based assessmentArchived samplesCancer researchExpressionTissue microarray technologyTissue samplesAbundanceSitu analysisAbundance of data