2024
Integrating phylogenies into single-cell RNA sequencing analysis allows comparisons across species, genes, and cells
Church S, Mah J, Dunn C. Integrating phylogenies into single-cell RNA sequencing analysis allows comparisons across species, genes, and cells. PLOS Biology 2024, 22: e3002633. PMID: 38787797, PMCID: PMC11125556, DOI: 10.1371/journal.pbio.3002633.Peer-Reviewed Original ResearchConceptsScRNA-seqPhylogenetic comparative approachCellular gene expressionScRNA-seq analysisSingle-cell RNA sequencingRNA sequencing analysisGene treesSpecies treeCell phylogenyPhylogenetic approachPhylogenetic treeEvolutionary historyPairwise alignmentSingle-cell RNA sequencing analysisSequence analysisCellular lifeRNA sequencingGene expressionGenesCell evolutionCell lineagesPhylogenySpeciesCell functionCellsCell type evolution reconstruction across species through cell phylogenies of single-cell RNA sequencing data
Mah J, Dunn C. Cell type evolution reconstruction across species through cell phylogenies of single-cell RNA sequencing data. Nature Ecology & Evolution 2024, 8: 325-338. PMID: 38182680, DOI: 10.1038/s41559-023-02281-9.Peer-Reviewed Original ResearchSingle-cell datasetsCell typesSingle-cell RNA sequencing dataFundamental evolutionary questionsCell type evolutionSister cell typesGene expression dynamicsRNA sequencing dataSingle-cell dataEvolutionary relationshipsEvolutionary questionsEvolutionary historyEvolutionary biologyExpression dynamicsPhylogenetic methodsPhylogenetic charactersMarker genesPhylogenySequencing dataEye cellsCladeType evolutionSpeciesCellsNon-myelinating Schwann cells
2021
The Evolutionary History of Siphonophore Tentilla: Novelties, Convergence, and Integration
Damian-Serrano A, Haddock S, Dunn C. The Evolutionary History of Siphonophore Tentilla: Novelties, Convergence, and Integration. Integrative Organismal Biology 2021, 3: obab019. PMID: 34355122, PMCID: PMC8331849, DOI: 10.1093/iob/obab019.Peer-Reviewed Original ResearchEvolutionary historyMorphological diversityComplex evolutionary historyBroad morphological diversityEvolutionary gainPhenotypic integrationEvolutionary timeHydrozoan cnidariansMorphological convergenceFunctional diversityMorphological charactersStructured diversityCharacter correlationsFeeding habitsPrey captureUnique biological structureSiphonophore speciesNematocyst typesTentillaDiversityKinematic diversitySpeciesBiological structuresNematocyst dischargeCnidarians