2004
Caspase-3 in Postnatal Retinal Development and Degeneration
Zeiss CJ, Neal J, Johnson EA. Caspase-3 in Postnatal Retinal Development and Degeneration. Investigative Ophthalmology & Visual Science 2004, 45: 964-970. PMID: 14985318, DOI: 10.1167/iovs.03-0439.Peer-Reviewed Original ResearchConceptsTerminal dUTP transferase nick end labelingPostnatal retinal developmentCaspase-3Photoreceptor degenerationRod deathMutant miceRetinal developmentInner nuclear layerDouble mutant miceNick end labelingLight microscopic levelRod photoreceptor developmentCell nuclear antigenNeonatal deathRetinal morphometryDysplastic lesionsRetinal dysplasiaNuclear layerPhotoreceptor protectionImmunohistochemical stainingRodent modelsFactor VIICaspase-3 activationNuclear antigenEnd labeling
2003
Pathogenesis of mouse hepatitis virus infection in gamma interferon-deficient mice is modulated by co-infection with Helicobacter hepaticus.
Compton SR, Ball-Goodrich LJ, Zeiss CJ, Johnson LK, Johnson EA, Macy JD. Pathogenesis of mouse hepatitis virus infection in gamma interferon-deficient mice is modulated by co-infection with Helicobacter hepaticus. Comparative Medicine 2003, 53: 197-206. PMID: 12784855.Peer-Reviewed Original ResearchConceptsIFN-gamma KO miceGamma interferon-deficient miceMouse hepatitis virusInterferon-deficient miceDevelopment of peritonitisKO miceH. hepaticusMultisystemic infectionHelicobacter hepaticusMouse hepatitis virus infectionHepatitis virus infectionAberrant immune responseSelf-limiting infectionMinimal pathologic changesMultifocal hepatic necrosisLater time pointsAcute necrotizingAcute peritonitisAcute phaseInflammatory lesionsImmunocompetent miceChronic infectionHepatic necrosisMHV infectionPathologic changes