Alefacept for the treatment of psoriasis and other dermatologic diseases
Strober B, Menon K. Alefacept for the treatment of psoriasis and other dermatologic diseases. Dermatologic Therapy 2007, 20: 270-276. PMID: 17970892, DOI: 10.1111/j.1529-8019.2007.00140.x.Peer-Reviewed Original ResearchConceptsT cellsSeverity Index (PASI) 75 responseMemory effector T cellsNovel biologic agentsLong-term remissionEffector T cellsTreatment of psoriasisAntigen presenting cellsPathophysiology of psoriasisCourse of therapyDimeric fusion proteinPASI 75Plaque psoriasisAdverse eventsPsoriasis AreaBiologic agentsMore patientsLabel useImmunologic activationPresenting cellsIntramuscular injectionDosing strategiesAlefaceptDermatologic diseasesPsoriasis