2005
Cognitive training of verbal memory using a dichotic listening paradigm: impact on symptoms and cognition
Fiszdon JM, Whelahan H, Bryson GJ, Wexler BE, Bell MD. Cognitive training of verbal memory using a dichotic listening paradigm: impact on symptoms and cognition. Acta Psychiatrica Scandinavica 2005, 112: 187-193. PMID: 16095473, DOI: 10.1111/j.1600-0447.2005.00565.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognitionDichotic Listening TestsFemaleHumansMaleMemoryNeuropsychological TestsTeachingVerbal BehaviorConceptsVerbal memoryAuditory hallucinationsDichotic listeningDL taskMemory training taskCognitive remediation trainingCognitive remediation programVerbal episodic memoryVerbal memory taskDichotic listening paradigmRemediation trainingCognitive trainingEpisodic memoryMemory taskTraining tasksRemediation programGeneral psychopathologyControl conditionMemoryTaskCognitionPsychiatric symptomsTrainingHierarchical trainingCurrent investigation
2004
Verbal memory in schizophrenia: additional evidence of subtypes having different cognitive deficits
Bruder GE, Wexler BE, Sage MM, Gil RB, Gorman JM. Verbal memory in schizophrenia: additional evidence of subtypes having different cognitive deficits. Schizophrenia Research 2004, 68: 137-147. PMID: 15099598, DOI: 10.1016/s0920-9964(03)00156-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionAuditory PerceptionCerebral CortexCognition DisordersDichotic Listening TestsDominance, CerebralFemaleFunctional LateralityHumansMaleMemory DisordersMental RecallNeuropsychological TestsPaired-Associate LearningPitch DiscriminationPsychiatric Status Rating ScalesSchizophreniaSchizophrenic PsychologyVerbal LearningWechsler ScalesConceptsVerbal memory deficitsMemory deficitsVerbal memoryWechsler Memory Scale-RevisedNonverbal cognitive functionsDifferent cognitive deficitsSerial position effectsVerbal materialVisual memoryNonverbal testsAuditory perceptionGeneralized deficitSelective deficitDichotic wordsHemispheric dominanceCognitive deficitsCognitive functionMemoryMedication statusHealthy controlsDeficitsOverall poor performancePosition effectsPoor performancePosition test
2002
Replication of a premenstrual decrease in right-ear advantage on language-related dichotic listening tests of cerebral laterality
Alexander GM, Altemus M, Peterson BS, Wexler BE. Replication of a premenstrual decrease in right-ear advantage on language-related dichotic listening tests of cerebral laterality. Neuropsychologia 2002, 40: 1293-1299. PMID: 11931932, DOI: 10.1016/s0028-3932(01)00220-2.Peer-Reviewed Original ResearchConceptsRight ear advantageNeutral wordsOverall right ear advantageNegative affective toneWord-word pairsDichotic word taskPremenstrual weekDichotic listening testPerceptual asymmetryWord taskAffective valenceTask demandsAffective toneHemispheric advantageTask performanceREA scoresPositive wordCerebral lateralityTest sessionsFunctional asymmetryListening testsWordsIdentical measuresSex differencesStimuli
2001
Neurocognitive Enhancement Therapy With Work Therapy: Effects on Neuropsychological Test Performance
Bell M, Bryson G, Greig T, Corcoran C, Wexler BE. Neurocognitive Enhancement Therapy With Work Therapy: Effects on Neuropsychological Test Performance. JAMA Psychiatry 2001, 58: 763-768. PMID: 11483142, DOI: 10.1001/archpsyc.58.8.763.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionCognitionCognition DisordersComputer-Assisted InstructionDichotic Listening TestsFeedbackFemaleFrontal LobeHumansMaleMemoryMultivariate AnalysisNeuropsychological TestsOccupational TherapyPsychomotor PerformancePsychotic DisordersSchizophreniaSchizophrenic PsychologyTeachingTreatment OutcomeConceptsNeurocognitive enhancement therapyEnhancement therapyWork therapyMental activityNeuropsychological testingLarge effect size improvementsExecutive function tasksNeuropsychological test performanceEffect size improvementsComputer-based trainingFunction tasksExecutive functionMemory performanceCognitive performanceNeuropsychological testsTraining tasksCognitive deficitsTest performanceComputer trainingCognitive dysfunctionIndependent outcome measureOccupational dysfunctionNatural contextSchizoaffective disorderMemory
1996
Affective reactivity of cognitive functioning and family history in schizophrenia
Docherty N, Grosh E, Wexler B. Affective reactivity of cognitive functioning and family history in schizophrenia. Biological Psychiatry 1996, 39: 59-64. PMID: 8719127, DOI: 10.1016/0006-3223(95)00102-6.Peer-Reviewed Original ResearchConceptsAffective reactivityNegative affectCognitive functioningRight ear advantageDichotic listening testThought disorder symptomsNegative stimuliNegative taskNeutral taskDisorder symptomsCognitive symptomsThought disorderFamily psychiatric historyOutpatient sampleListening testsAffectSchizophreniaFunctioningTaskSchizophrenic inpatientsPsychiatric historyDisordersStimuliSymptomsFindings
1995
Behavioral laterality in individuals with Gilles de la Tourette's syndrome and basal ganglia alterations: A preliminary report
Yazgan M, Peterson B, Wexler B, Leckman J. Behavioral laterality in individuals with Gilles de la Tourette's syndrome and basal ganglia alterations: A preliminary report. Biological Psychiatry 1995, 38: 386-390. PMID: 8547458, DOI: 10.1016/0006-3223(94)00302-j.Peer-Reviewed Original ResearchConceptsGTS patientsTourette syndromeIntact basal ganglia functionGilles de la Tourette's syndromeGTS subjectsAdult GTS patientsBasal ganglia alterationsBasal ganglia functionLa Tourette's syndromePrevious MRI studiesNeuropsychological measuresFunctional asymmetryGanglia functionTic symptomsNormal controlsMRI studiesSyndromePreliminary reportPatientsNeuropsychological tasksFunctional significanceSubjectsBehavioral lateralitySymptomsAbnormalitiesFunctional significance of individual variations in callosal area
Yazgan M, Wexler B, Kinsbourne M, Peterson B, Leckman J. Functional significance of individual variations in callosal area. Neuropsychologia 1995, 33: 769-779. PMID: 7675166, DOI: 10.1016/0028-3932(95)00018-x.Peer-Reviewed Original ResearchConceptsCallosal areaCorpus callosumMidsagittal cross-sectional areaDual-task interferenceDual-task performanceTime-sharing abilityBehavioral lateralityInterhemispheric connectionsWord listeningTask interferenceLine bisectionNormal adultsCross-sectional areaHemisphere conditionsBias testCallosumLateralityNormal variationFunctional significanceIndividual variationAbnormal laterality in schizophrenics and their parents
Grosh E, Docherty N, Wexler B. Abnormal laterality in schizophrenics and their parents. Schizophrenia Research 1995, 14: 155-160. PMID: 7710996, DOI: 10.1016/0920-9964(94)00033-5.Peer-Reviewed Original ResearchConceptsRight ear advantageNegative emotional valenceEmotional valenceHemispheric activationLower right-ear advantagesPositive emotional valenceLateralized cerebral functionsLeft-hemispheric activationDichotic word testNeutral wordsPerceptual asymmetryPerceptual advantageWord TestDichotic testsEar advantageValenceWordsParentsAbnormal lateralitySchizophrenic offspringSchizophrenicsSchizophrenic patientsCerebral functionSame subjectsLaterality
1994
Decreased perceptual sensitivity to emotion-evoking stimuli in depression
Wexler B, Levenson L, Warrenburg S, Price L. Decreased perceptual sensitivity to emotion-evoking stimuli in depression. Psychiatry Research 1994, 51: 127-138. PMID: 8022947, DOI: 10.1016/0165-1781(94)90032-9.Peer-Reviewed Original ResearchConceptsFacial displaysOwn faceNegative emotion-related wordsEmotion-evoking stimuliEmotion-related wordsDichotic listening paradigmEmotion-related stimuliNegative facial displaysNormal cognitive processingNeutral wordsAutomatic mimicryCognitive processingPerceptual sensitivityFacial mimicryNegative wordsEmotional responsesDichotic testsSelective perceptionDepressed patientsStimuliWordsHealthy controlsEmotionsFaceSuch measures
1992
EEG and EMG responses to emotion-evoking stimuli processed without conscious awareness
Wexler B, Warrenburg S, Schwartz G, Janer L. EEG and EMG responses to emotion-evoking stimuli processed without conscious awareness. Neuropsychologia 1992, 30: 1065-1079. PMID: 1484602, DOI: 10.1016/0028-3932(92)90099-8.Peer-Reviewed Original ResearchConceptsConscious awarenessGreater right hemisphere activityEmotion-evoking stimuliEmotion-specific responsesRight hemisphere activityEEG alpha activityRight frontal regionNeutral wordsConscious processingStimulus pairsAuditory perceptsHemisphere activityPositive feelingsFrontal regionsWordsAlpha activityStimuliEEGPerceptAwarenessCorrugatorFeelingsThoughtProcessingEMG responsesDichotic listening in monozygotic twins discordant and concordant for schizophrenia
Ragland J, Goldberg T, Wexler B, Gold J, Torrey E, Weinberger D. Dichotic listening in monozygotic twins discordant and concordant for schizophrenia. Schizophrenia Research 1992, 7: 177-183. PMID: 1515379, DOI: 10.1016/0920-9964(92)90048-a.Peer-Reviewed Original ResearchConceptsDichotic listeningSmaller right-ear advantageAllocation of attentionDichotic listening scoresRight ear advantageDichotic listening testNeutral wordsEmotional wordsEmotional stimuliLateralized representationEar advantageLeft hemisphereListening scoresWord versionHandedness scoresListening tests
1991
Cerebral laterality, perception of emotion, and treatment response in obsessive-compulsive disorder
Wexler B, Goodman W. Cerebral laterality, perception of emotion, and treatment response in obsessive-compulsive disorder. Biological Psychiatry 1991, 29: 900-908. PMID: 2049488, DOI: 10.1016/0006-3223(91)90056-r.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAuditory PerceptionCerebellumDichotic Listening TestsEarEmotionsFemaleFunctional LateralityHumansLanguageMaleMiddle AgedObsessive-Compulsive DisorderConceptsObsessive-compulsive disorderEmotion-related wordsNeutral wordsCerebral lateralityLower right-ear advantagesPerception of emotionPositive emotional valenceRight ear advantageDichotic listening testEmotional valenceStimulus pairsOCD patientsListening testsWordsHealthy controlsDepressed patientsSerotonin reuptake inhibitorsLateralityEmotionsDisordersReuptake inhibitorsSevere illnessTreatment responseValencePatientsCerebral laterality, symptoms, and diagnosis in psychotic patients
Wexler B, Giller E, Southwick S. Cerebral laterality, symptoms, and diagnosis in psychotic patients. Biological Psychiatry 1991, 29: 103-116. PMID: 1995082, DOI: 10.1016/0006-3223(91)90039-o.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBrainDepressive DisorderDichotic Listening TestsFunctional LateralityHumansMaleMiddle AgedProhibitinsPsychotic DisordersSchizophreniaConceptsRight ear advantageLower right-ear advantagesManic patientsPositive symptomsNegative symptomsCerebral lateralitySubset of patientsDisease-related decreaseWord TestSchizoaffective patientsSymptomatic inpatientsDepressed patientsHealthy controlsSymptom remissionSchizophrenic patientsMood disturbancePatientsMore symptomsPsychotic patientsSymptomsDichotic word testLeft hemisphereEar advantageThought disorderSimilar changes
1990
Within-modal and cross-modal consistency in the direction and magnitude of perceptual asymmetry
Wexler B, King G. Within-modal and cross-modal consistency in the direction and magnitude of perceptual asymmetry. Neuropsychologia 1990, 28: 71-80. PMID: 2314565, DOI: 10.1016/0028-3932(90)90087-5.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionDichotic Listening TestsDominance, CerebralFemaleHumansMaleMiddle AgedPaired-Associate LearningPhoneticsReadingSpeech Perception
1989
Possible Subtypes of Affective Disorder Suggested by Differences in Cerebral Laterality and Testosterone: A Preliminary Report
Wexler B, Mason J, Giller E. Possible Subtypes of Affective Disorder Suggested by Differences in Cerebral Laterality and Testosterone: A Preliminary Report. JAMA Psychiatry 1989, 46: 429-433. PMID: 2712661, DOI: 10.1001/archpsyc.1989.01810050043007.Peer-Reviewed Original ResearchConceptsSerum testosterone levelsDichotic listening testAffective disordersTestosterone levelsMean serum testosterone levelCerebral lateralityTime of admissionPathophysiological heterogeneityDiagnostic groupsSymptom severityPreliminary reportPossible subtypesHemisphere functionDisordersSubgroupsLateralityMeaningful subgroupsPositive correlationNegative correlationGroupHospitalizationPatientsAdmissionPathogenesesTestosteroneNeuropsychological correlates of menstrual mood changes.
Altemus M, Wexler B, Boulis N. Neuropsychological correlates of menstrual mood changes. Psychosomatic Medicine 1989, 51: 329-336. PMID: 2734425, DOI: 10.1097/00006842-198905000-00007.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultDichotic Listening TestsFemaleFollicular PhaseHumansMenstrual CycleMiddle AgedPremenstrual SyndromePsychomotor AgitationChanges in perceptual asymmetry with the menstrual cycle
Altemus M, Wexler B, Boulis N. Changes in perceptual asymmetry with the menstrual cycle. Neuropsychologia 1989, 27: 233-240. PMID: 2927632, DOI: 10.1016/0028-3932(89)90174-7.Peer-Reviewed Original ResearchConceptsRight ear advantageRepressive personality stylePerceptual asymmetryPersonality stylesUsual right ear advantageLanguage-related stimuliDichotic listening testPsychological featuresNeuropsychological findingsEar advantagePostmenstrual phaseMenstrual cycleListening testsStyleStimuliAsymmetryFindings
1988
Sex differences in change over time in perceptual asymmetry
Wexler B, Lipman A. Sex differences in change over time in perceptual asymmetry. Neuropsychologia 1988, 26: 943-946. PMID: 3194057, DOI: 10.1016/0028-3932(88)90063-2.Peer-Reviewed Original Research
1986
Effects of emotion on perceptual asymmetry: Interactions with personality
Wexler B, Schwartz G, Warrenburg S, Servis M, Tarlatzis I. Effects of emotion on perceptual asymmetry: Interactions with personality. Neuropsychologia 1986, 24: 699-710. PMID: 3785657, DOI: 10.1016/0028-3932(86)90009-6.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultDichotic Listening TestsEmotionsFemaleFunctional LateralityHumansMaleMiddle AgedPerceptionPersonalityConceptsPerceptual asymmetryAnxious subjectsEffects of emotionHigh-anxious subjectsLow-anxious subjectsLeft-hemisphere functionDichotic word testDichotic listening testWord TestEmotional qualityLeft hemisphereEmotionsPersonality characteristicsInformation processingPersonality groupsBrain statesListening testsNeutral testWordsHemispherePersonalitySubjectsProcessingTestAsymmetry
1985
Dichotic listening tests in studying brain-behavior relationships
Wexler B, Halwes T. Dichotic listening tests in studying brain-behavior relationships. Neuropsychologia 1985, 23: 545-559. PMID: 4033907, DOI: 10.1016/0028-3932(85)90008-9.Peer-Reviewed Original ResearchConceptsPerceptual asymmetryBrain-behavior relationshipsConcurrent visual taskDichotic listening testNonsense Syllable TestCVC wordsPhonemic cuesWord TestVisual tasksDichotic wordsTest-retest reliabilityListening testsAssociative functionsWordsPA measuresSpecific waysDifferent testsConsonantsCuesWAISRelationshipReceptivePhysiological basisTaskEnglish