2006
Neuropsychological deficits in nonsmokers with schizophrenia: Effects of a nicotinic antagonist
Sacco KA, Termine A, Dudas MM, Seyal AA, Allen TM, Vessicchio JC, Wexler BE, George TP. Neuropsychological deficits in nonsmokers with schizophrenia: Effects of a nicotinic antagonist. Schizophrenia Research 2006, 85: 213-221. PMID: 16678390, DOI: 10.1016/j.schres.2006.03.025.Peer-Reviewed Original ResearchConceptsWisconsin Card Sorting TestContinuous Performance TestControl nonsmokersNeuropsychological performanceStroop Color-Word TestNeuropsychological deficitsNicotinic acetylcholine receptor systemAcetylcholine receptor systemPosition testVisuospatial working memoryCigarette smokingAntagonist mecamylamineNicotinic antagonistsNeuropsychological dysfunctionNAChR blockadeNonsmokersSchizophrenia diagnosisColor-Word TestMecamylamineReceptor systemNeuropsychological assessmentSchizophreniaCard Sorting TestCounterbalanced designTest week
2005
Differences in performance and learning proficiency on the Wisconsin Card Sorting Test in schizophrenia: Do they reflect distinct neurocognitive subtypes with distinct functional profiles?
Kurtz MM, Wexler BE. Differences in performance and learning proficiency on the Wisconsin Card Sorting Test in schizophrenia: Do they reflect distinct neurocognitive subtypes with distinct functional profiles? Schizophrenia Research 2005, 81: 167-171. PMID: 16243489, DOI: 10.1016/j.schres.2005.09.003.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdultAttentionCognition DisordersCuesDiscrimination LearningFemaleHumansLearning DisabilitiesMaleMemory, Short-TermMiddle AgedNeuropsychological TestsPractice, PsychologicalProblem SolvingPsychometricsPsychomotor PerformanceReaction TimeSchizophreniaSchizophrenic PsychologyConceptsWisconsin Card Sorting TestUCSD Performance-based Skills AssessmentCard Sorting TestSorting TestComprehensive neurocognitive test batteryPerformance-Based Skills AssessmentDifferent neurocognitive profilesNeurocognitive test batteryPerformance-based measuresBehavioral treatment interventionsSecond measureNeurocognitive subtypesNeurocognitive profileMotor sequencingWCST performancePoor learnersTest batteryGood learnersDistinct functional profilesSubtyping of patientsTreatment interventionsIndependent measuresLearnersSkills assessmentGreater functional capacity
2004
Neuropsychological deficits are associated with smoking cessation treatment failure in patients with schizophrenia
Dolan SL, Sacco KA, Termine A, Seyal AA, Dudas MM, Vessicchio JC, Wexler BE, George TP. Neuropsychological deficits are associated with smoking cessation treatment failure in patients with schizophrenia. Schizophrenia Research 2004, 70: 263-275. PMID: 15329302, DOI: 10.1016/j.schres.2004.01.006.Peer-Reviewed Original ResearchConceptsNon-psychiatric control smokersTreatment failureStroop Color-Word TestContinuous Performance TestNeuropsychological deficitsControl smokersWisconsin Card Sorting TestPlacebo-controlled trialAtypical antipsychotic treatmentCessation treatmentAntipsychotic treatmentCessation interventionsCigarette smokingDepressive symptomsPharmacological agentsColor-Word TestSmokingNeuropsychological assessmentNeuropsychological performanceCard Sorting TestVisuospatial Working Memory TaskGreater deficitsPreliminary dataSmokersPatientsThe Penn Conditional Exclusion Test (PCET): relationship to the Wisconsin Card Sorting Test and work function in patients with schizophrenia
Kurtz MM, Wexler BE, Bell MD. The Penn Conditional Exclusion Test (PCET): relationship to the Wisconsin Card Sorting Test and work function in patients with schizophrenia. Schizophrenia Research 2004, 68: 95-102. PMID: 15037343, DOI: 10.1016/s0920-9964(03)00179-8.Peer-Reviewed Original ResearchConceptsPenn Conditional Exclusion TestWisconsin Card Sorting TestWork Behavior InventoryCard Sorting TestExecutive functionSorting TestDivergent validityExecutive function measuresNew computerized measureStandard neuropsychological measuresMeasures of cooperativenessCriterion-related validityVerbal learningNeuropsychological measuresVisual sequencingComputerized measuresPsychomotor speedVocational settingsBehavior InventoryVocational functionAnalogous measuresSpecific dimensionsWork skillsTotal errorWork quality