2010
Memory profiles in schizophrenia: Categorization validity and stability
Bell MD, Johannesen JK, Greig TC, Wexler BE. Memory profiles in schizophrenia: Categorization validity and stability. Schizophrenia Research 2010, 118: 26-33. PMID: 20085855, PMCID: PMC3699867, DOI: 10.1016/j.schres.2009.12.037.Peer-Reviewed Original ResearchConceptsSocial cognitive domainsMemory profileCognitive domainsHopkins Verbal LearningCluster analytic techniquesSocial cognitionVerbal learningVerbal memorySubcortical impairmentNeuropsychological assessmentCommunity mental health centerCortical impairmentMental health centersSchizoaffective disorderMotor speedCurrent studySchizophreniaIllness characteristicsMemoryUrban community mental health centerImpairmentSimple decision rulesCognitionCluster analysisCluster groups
2008
Predictors of change in life skills in schizophrenia after cognitive remediation
Kurtz MM, Seltzer JC, Fujimoto M, Shagan DS, Wexler BE. Predictors of change in life skills in schizophrenia after cognitive remediation. Schizophrenia Research 2008, 107: 267-274. PMID: 19006657, PMCID: PMC3399665, DOI: 10.1016/j.schres.2008.10.014.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdultAttentionCognition DisordersComprehensionComputer-Assisted InstructionFemaleHumansInhibition, PsychologicalMemory, Short-TermMiddle AgedNeuropsychological TestsProblem SolvingPrognosisPsychiatric Status Rating ScalesPsychometricsPsychomotor PerformanceRemedial TeachingSchizophreniaSchizophrenic PsychologySocializationSoftwareVerbal LearningYoung AdultConceptsCognitive remediationAuditory attentionPerformance-based measuresRemediation interventionsComputer-assisted cognitive remediationLife skillsCognitive remediation interventionsSustained auditory attentionEveryday life skillsTreatment-related improvementTreatment process variablesOutpatient rehabilitation treatmentPredictors of changeMeasures of symptomsVerbal abilityVerbal learningTreatment outcome measuresNeurocognitive variablesNeurocognitive functionMemoryNegative symptomsSchizoaffective disorderPredictor studiesCurrent studySchizophrenia
2007
Neurocognitive enhancement therapy with work therapy in schizophrenia: 6-month follow-up of neuropsychological performance
Bell M, Fiszdon J, Greig T, Wexler B, Bryson G. Neurocognitive enhancement therapy with work therapy in schizophrenia: 6-month follow-up of neuropsychological performance. The Journal Of Rehabilitation Research And Development 2007, 44: 761. PMID: 17943687, DOI: 10.1682/jrrd.2007.02.0032.Peer-Reviewed Original ResearchConceptsNeurocognitive enhancement therapyWork therapyEnhancement therapyExecutive function tasksComputer-based trainingNonverbal memoryFunction tasksExecutive functionNeuropsychological performanceNeuropsychological testsNeuropsychological assessmentCognitive deficitsCompletion of trainingNeuropsychological improvementOccupational dysfunctionMemorySchizoaffective disorderCurrent studySchizophreniaTrainingJob placementWork activitiesActive interventionTaskAnalysis of variance
2006
Computer-assisted cognitive remediation in schizophrenia: What is the active ingredient?
Kurtz MM, Seltzer JC, Shagan DS, Thime WR, Wexler BE. Computer-assisted cognitive remediation in schizophrenia: What is the active ingredient? Schizophrenia Research 2006, 89: 251-260. PMID: 17070671, PMCID: PMC2095777, DOI: 10.1016/j.schres.2006.09.001.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionCognition DisordersComputer User TrainingComputer-Assisted InstructionFemaleHumansMaleMemory, Short-TermMental RecallMiddle AgedNeuropsychological TestsPattern Recognition, VisualProblem SolvingReaction TimeRemedial TeachingSchizophreniaSchizophrenic LanguageSchizophrenic PsychologySpeech PerceptionConceptsComputer-assisted cognitive remediationTraining control conditionCognitive remediationNeurocognitive functionComprehensive neuropsychological test batteryCognitive remediation interventionsCognitive remediation trainingSpatial episodic memoryControl conditionNeuropsychological test batteryEpisodic memoryComplex behavioral treatmentsBody of researchCognitive stimulationRemediation interventionsCognitive challengesNeurocognitive testsProcessing speedBehavioral treatmentTest batteryMemoryExperimental interventionSchizophreniaNon-specific stimulationIntervention
2005
Cognitive training of verbal memory using a dichotic listening paradigm: impact on symptoms and cognition
Fiszdon JM, Whelahan H, Bryson GJ, Wexler BE, Bell MD. Cognitive training of verbal memory using a dichotic listening paradigm: impact on symptoms and cognition. Acta Psychiatrica Scandinavica 2005, 112: 187-193. PMID: 16095473, DOI: 10.1111/j.1600-0447.2005.00565.x.Peer-Reviewed Original ResearchConceptsVerbal memoryAuditory hallucinationsDichotic listeningDL taskMemory training taskCognitive remediation trainingCognitive remediation programVerbal episodic memoryVerbal memory taskDichotic listening paradigmRemediation trainingCognitive trainingEpisodic memoryMemory taskTraining tasksRemediation programGeneral psychopathologyControl conditionMemoryTaskCognitionPsychiatric symptomsTrainingHierarchical trainingCurrent investigationNeurocognitive enhancement therapy with work therapy: Productivity outcomes at 6- and 12-month follow-ups
Bell MD, Bryson GJ, Greig TC, Fiszdon JM, Wexler BE. Neurocognitive enhancement therapy with work therapy: Productivity outcomes at 6- and 12-month follow-ups. The Journal Of Rehabilitation Research And Development 2005, 42: 829. PMID: 16680620, DOI: 10.1682/jrrd.2005.03.0061.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognitive Behavioral TherapyCombined Modality TherapyFollow-Up StudiesHumansMiddle AgedNeuropsychological TestsOdds RatioPatient ComplianceProbabilityPsychiatric Status Rating ScalesPsychotic DisordersRehabilitation, VocationalRisk AssessmentSchizophreniaTask Performance and AnalysisTime FactorsTreatment OutcomeConceptsNeurocognitive enhancement therapyWork therapyCognitive trainingEnhancement therapyComputerized cognitive trainingExecutive functionWork outcomesCommunity mental health centerDiagnosis of schizophreniaMental health centersMental hygiene clinicSchizoaffective disorderRandom effects analysisNet trainingProductivity outcomesTrainingRehabilitation programSchizophreniaMore hoursMemoryPresent studyDisordersOutcomesEffect analysisFindings
2004
Verbal memory in schizophrenia: additional evidence of subtypes having different cognitive deficits
Bruder GE, Wexler BE, Sage MM, Gil RB, Gorman JM. Verbal memory in schizophrenia: additional evidence of subtypes having different cognitive deficits. Schizophrenia Research 2004, 68: 137-147. PMID: 15099598, DOI: 10.1016/s0920-9964(03)00156-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionAuditory PerceptionCerebral CortexCognition DisordersDichotic Listening TestsDominance, CerebralFemaleFunctional LateralityHumansMaleMemory DisordersMental RecallNeuropsychological TestsPaired-Associate LearningPitch DiscriminationPsychiatric Status Rating ScalesSchizophreniaSchizophrenic PsychologyVerbal LearningWechsler ScalesConceptsVerbal memory deficitsMemory deficitsVerbal memoryWechsler Memory Scale-RevisedNonverbal cognitive functionsDifferent cognitive deficitsSerial position effectsVerbal materialVisual memoryNonverbal testsAuditory perceptionGeneralized deficitSelective deficitDichotic wordsHemispheric dominanceCognitive deficitsCognitive functionMemoryMedication statusHealthy controlsDeficitsOverall poor performancePosition effectsPoor performancePosition test
2003
Cognitive remediation of working memory deficits: durability of training effects in severely impaired and less severely impaired schizophrenia
Bell M, Bryson G, Wexler BE. Cognitive remediation of working memory deficits: durability of training effects in severely impaired and less severely impaired schizophrenia. Acta Psychiatrica Scandinavica 2003, 108: 101-109. PMID: 12823166, DOI: 10.1034/j.1600-0447.2003.00090.x.Peer-Reviewed Original ResearchConceptsNeurocognitive enhancement therapyWork therapyCognitive remediationTraining effectsSocial information processingCognitive training exercisesExecutive functionMemory performanceEnhancement therapyMemory deficitsInformation processingSeverity of impairmentDuration of trainingGreater improvementSchizoaffective disorderMemoryParticipantsTraining exercisesMost participantsImpairment severitySchizophreniaTrainingDuration of effectSeverity groupsDeficitsNormalization of working memory in schizophrenia following cognitive remediation: Durability of effects
Fiszdon J, Bryson G, Wexler B, Bell M. Normalization of working memory in schizophrenia following cognitive remediation: Durability of effects. Schizophrenia Research 2003, 60: 322. DOI: 10.1016/s0920-9964(03)80282-7.Peer-Reviewed Original Research
2001
Neurocognitive Enhancement Therapy With Work Therapy: Effects on Neuropsychological Test Performance
Bell M, Bryson G, Greig T, Corcoran C, Wexler BE. Neurocognitive Enhancement Therapy With Work Therapy: Effects on Neuropsychological Test Performance. JAMA Psychiatry 2001, 58: 763-768. PMID: 11483142, DOI: 10.1001/archpsyc.58.8.763.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionCognitionCognition DisordersComputer-Assisted InstructionDichotic Listening TestsFeedbackFemaleFrontal LobeHumansMaleMemoryMultivariate AnalysisNeuropsychological TestsOccupational TherapyPsychomotor PerformancePsychotic DisordersSchizophreniaSchizophrenic PsychologyTeachingTreatment OutcomeConceptsNeurocognitive enhancement therapyEnhancement therapyWork therapyMental activityNeuropsychological testingLarge effect size improvementsExecutive function tasksNeuropsychological test performanceEffect size improvementsComputer-based trainingFunction tasksExecutive functionMemory performanceCognitive performanceNeuropsychological testsTraining tasksCognitive deficitsTest performanceComputer trainingCognitive dysfunctionIndependent outcome measureOccupational dysfunctionNatural contextSchizoaffective disorderMemory
1999
California Verbal Learning Test practice effects in a schizophrenia sample
Hawkins K, Wexler B. California Verbal Learning Test practice effects in a schizophrenia sample. Schizophrenia Research 1999, 39: 73-78. PMID: 10480669, DOI: 10.1016/s0920-9964(99)00015-8.Peer-Reviewed Original ResearchConceptsPractice effectsCalifornia Verbal Learning TestVerbal Learning TestTest practice effectsLearning TestWeek 10Sample of personsNew learningSchizophrenia sampleLater performancePrior exposureNon-pharmacological interventionsSerial performanceSample of patientsClinical circumstancesWeek 14Psychiatric statusLearningSchizophreniaCVLTExact natureMemoryConsiderable retentionLarge effectExposure
1997
Normal neurocognitive performance after extended practice in patients with schizophrenia
Wexler B, Hawkins K, Rounsaville B, Anderson M, Sernyak M, Green M. Normal neurocognitive performance after extended practice in patients with schizophrenia. Schizophrenia Research 1997, 26: 173-180. PMID: 9323348, DOI: 10.1016/s0920-9964(97)00053-4.Peer-Reviewed Original ResearchConceptsWeeks of practiceSpecific neurocognitive tasksNormal neurocognitive performancePerformance of patientsImplicit learningMemory taskNeurocognitive tasksNeurocognitive performanceExtended practiceSame taskMotor tasksNeurocognitive improvementDifficulty levelOngoing instructionPerformance declineBase payTaskSupranormal performanceSchizophreniaHealthy controlsMemoryLearningInstructionTrainingPerformance
1992
The selective perception and recognition of single words from competing dichotic stimulus pairs
Bonanno G, Wexler B. The selective perception and recognition of single words from competing dichotic stimulus pairs. Consciousness And Cognition 1992, 1: 241-264. DOI: 10.1016/1053-8100(92)90064-h.Peer-Reviewed Original ResearchAffective valenceSelective perceptionTwo-alternative forced-choice taskNegative affective valenceRecognition of wordsForced-choice taskUnconscious processingWord pairsStimulus pairsCognitive activityPerception effectSingle wordsDichotic presentationInitial consonantsIntertrial intervalControl taskRanking taskWordsTaskValencePerceptionRecognitionConsonantsMemoryAcoustic properties