2004
Functional MRI changes before and after onset of reported emotions
Prohovnik I, Skudlarski P, Fulbright RK, Gore JC, Wexler BE. Functional MRI changes before and after onset of reported emotions. Psychiatry Research 2004, 132: 239-250. PMID: 15664795, DOI: 10.1016/j.pscychresns.2004.03.005.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingEmotional responsesConscious emotional experienceBrain regionsBrain-imaging studiesSubjective emotional responsesNegative emotional responsesFace social interactionsSuperior temporal gyrusMiddle frontal gyrusEmotion-related behaviorsDistinctive brain regionsMultiple brain regionsCognitive tasksEvoked emotionHealthy young adultsNeural correlatesSad conditionEmotional experienceFrontal gyrusReported onsetEmotional stimulationTemporal gyrusSensory regionsSocial interaction
2000
Preliminary Evidence of Improved Verbal Working Memory Performance and Normalization of Task-Related Frontal Lobe Activation in Schizophrenia Following Cognitive Exercises
Wexler BE, Anderson M, Fulbright RK, Gore JC. Preliminary Evidence of Improved Verbal Working Memory Performance and Normalization of Task-Related Frontal Lobe Activation in Schizophrenia Following Cognitive Exercises. American Journal Of Psychiatry 2000, 157: 1694-1697. PMID: 11007730, DOI: 10.1176/appi.ajp.157.10.1694.Peer-Reviewed Original ResearchConceptsLeft inferior frontal cortexTask-related activationVerbal memory taskInferior frontal cortexMemory performanceMemory taskCognitive exercisesMemory exercisesNonverbal memory performanceWorking Memory PerformanceVerbal memory deficitsVerbal memory dysfunctionFrontal lobe activationRegional brain activationFrontal cortexSame brain regionsBrain activationTraining periodMemory deficitsMemory dysfunctionBrain regionsPreliminary evidenceBehavioral aspectsTaskSchizophrenia
1998
Functional MR imaging of regional brain responses to pleasant and unpleasant odors.
Fulbright RK, Skudlarski P, Lacadie CM, Warrenburg S, Bowers AA, Gore JC, Wexler BE. Functional MR imaging of regional brain responses to pleasant and unpleasant odors. American Journal Of Neuroradiology 1998, 19: 1721-6. PMID: 9802496, PMCID: PMC8337499.Peer-Reviewed Original ResearchConceptsFunctional MR imagingArea 8BA 6MR imagingBrodmann area 8Human cerebral cortexRegional brain responsesMedial temporal lobeTemporal brain regionsLeft BA 6Independent t-testCerebral cortexTemporal lobeBA 32Cortical areasLeft insulaAnterior temporal brain regionsBrain regionsOrbitofrontal cortexNormal adultsIsovaleric acidOlfactory networkMore activityAir trialsBrain responses
1997
An fMRI study of the human cortical motor system response to increasing functional demands
Wexler B, Fulbright R, Lacadie C, Skudlarski P, Kelz M, Constable R, Gore J. An fMRI study of the human cortical motor system response to increasing functional demands. Magnetic Resonance Imaging 1997, 15: 385-396. PMID: 9223039, DOI: 10.1016/s0730-725x(96)00232-9.Peer-Reviewed Original ResearchConceptsMotor-sensory areasSupplementary motor areaFunctional magnetic resonance imagingPremotor areasMotor areaMultiple motor areasComplexity of movementCortical motor systemRight-hand finger movementsIndex finger movementsFinger movementsMagnetic resonance imagingInferior parietal areasConsistent lateralizationResonance imagingBrain regionsActivation changesMotor system responsesParietal areasHand finger movementsPreliminary reproducibility studyFMRI studySignificant main effectWeek periodGreater increase
1991
Failure at task-specific regional brain activation: new conceptualization of a disease entity
Wexler B. Failure at task-specific regional brain activation: new conceptualization of a disease entity. Journal Of Neuropsychiatry 1991, 3: 94-98. PMID: 7580183, DOI: 10.1176/jnp.3.1.94.Peer-Reviewed Original ResearchConceptsNormal brain functionSymptom-based diagnosisRegional brain activationBrain functionBrain activationGroup of patientsCurrent symptom-based diagnosesMultiple brain regionsSpecific anatomic locationsClinical courseEtiologic diagnosisDisease entityAnatomic locationClinical practiceCurrent diagnostic systemsNew treatmentsPathophysiological processesBrain regionsDSM-IIIOrgan systemsDiagnosisBranches of medicinePhysiological dysfunctionNormal functionPatients
1986
A Model of Brain Function: Its Implications for Psychiatric Research
Wexler B. A Model of Brain Function: Its Implications for Psychiatric Research. The British Journal Of Psychiatry 1986, 148: 357-362. PMID: 3730703, DOI: 10.1192/bjp.148.4.357.Peer-Reviewed Original Research